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AQA A Level Biology- Model Questions and Answers Latest (2023 / 2024) (Verified Answers) $12.49   Add to cart

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AQA A Level Biology- Model Questions and Answers Latest (2023 / 2024) (Verified Answers)

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AQA A Level Biology- Model Questions and Answers Latest (2023 / 2024) (Verified Answers)

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  • August 3, 2023
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  • 2023/2024
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AQA A Level Biology- Model Answers

1. DNA Replication: DNA helicase breaks hydrogen bonds. Each strand

acts as a template. Free nucleotides attach. Complementary base

pairing occurs- AT and

CG. DNA polymerase joins nucleotides. Hydrogen bonds reform. Semi-

conservative replication- new DNA molecule contains one old and one

new strand

2. Transcription: DNA helicase breaks hydrogen bonds between DNA

strands. One strand acts as a template. RNA nucleotides attract to

exposed complementary bases on DNA. RNA polymerase joins

nucleotides together. Pre-mRNA spliced to remove introns

3. Translation: Ribosomes are sites of protein synthesis. mRNA strand

attaches to ribosome. Each mRNA codon codes for specific amino acid.

Anti-codons on tRNA match up with codon on mRNA and form

complementary base pairs. Peptide bonds formed between adjacent

amino acids. Polypeptide chain formed

4. Protein Structure: Polymer of amino acids joined by peptide bonds

formed by condensation reaction.

• Primary structure is the order of amino acids. •Secondary is folding


,of polypeptide chain due to hydrogen bonding.

• Tertiary structure is polypeptide chain folded into 3D shape due to

hydrogen and ionic bonding and disulphide bridges.

• Quaternary is 2 or more polypeptide chains

5. Protein Digestion in Human Gut: Hydrolysis of peptide bonds.

• Endopeptidases break polypeptides into smaller peptide chains

• Exopeptidases remove terminal amino acids

• Dipeptidases hydrolyse dipeptidases into amino acids

6. DNA Hybridisation/ Immunology: Break hydrogen bonds. Mix DNA

strand of different species. Temperature required to break hydrogen

bonds indicates relation- ship. Compare DNA sequence of nucleotides.

Compare sequence of amino acids. Inject serum into animal. Obtain

antibodies. Add serum from other species. Amount of precipitate

formed indicates relationship

7. Structure of DNA related to its function: Sugar phosphate backbone

providing strength. Long molecule so can store lots of information.

Helical so compact. Dou- ble-stranded so semi-conservative replication

can occur. Weak Hydrogen bonds for unzipping during replication. Many

hydrogen bonds so stable and strong



,8. Vaccines: Vaccine contains dead pathogen. Macrophage presents

antigen on its surface. T cell with complementary receptor protein binds

to antigen. Stimulates

B cells with complementary antibody on surface. B cell secretes

antibodies. They divide to form clones and memory cells. Secondary

exposure, become active and antibodies produced faster. Pathogen

destroyed before toxins produced or cells damaged. Herd effect means

there are fewer people to pass on disease.






, 9. Active and Passive Immunity: •Active involves memory cells whereas

passive doesn't. •Active involves production of antibody by plasma

cells or memory cells. Passive involves antibody introduced into body

from outside.

• Active is long-term as antibody is produced in response to antigen.

Passive is short term as antibody is broken down.

• Active takes time to work whereas passive is fast-acting.

10.Starch and Cellulose Related to Function: Starch:

• has helical shape so compact

• large and insoluble so osmotically inactive

• Branched so glucose easily released for respiration. Large so can't

leave via cell membrane


Cellulose:

• long, straight unbranched chains of ²-glucose

• joined by hydrogen bonding

• forms fibrils

• provides rigidity and strength

11.Enzyme Mutation: Mutation in nucleotide sequence of gene causes

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