NBME Exam Questions with Correct Answers

HGPRT function (Purine salvage pathway Correct Answer converts hypoxanthine to IMP converts guanine to GMP acute tubular necrosis Correct Answer ischemia or nephrotoxic substances compartment syndrome - muscle necrosis - rhabdomyolysis - acute tubular necrosis destruction of hemidesmosomes results in Correct Answer blisters anchoring fibrils of basal keratinocytes in epidermis to dermis jejunum compared to ileum Correct Answer feathery appearance with contrast, more surface area Hereditary spherocytosis Correct Answer RBC membrane defect in tethering proteins: spectrin/band 3.1/ankyrin, membranes fragile and less distendiblee Hemolytic anemia, jauncide, and splenomegaly often after URIs Low haptoglobin Correct Answer means being consumed by binding hemoglobin in blood first line treatment adhd Correct Answer stimulant = amphetamine salts, methylphenidate increase release of dopamine and norepi hypoxemia with normal A-a gradient Correct Answer high altitude, hypoventilation 5-15 ADP in platelet plug formation Correct Answer causes aggregation by acting on P2Y receptors Measles (Rubeola) presentation, type of virus, where it enters body Correct Answer What negative sense RNA virus is associated with cough, coryza, and conjunctivitis with photophobia? replicates in respiratory epithelium Measles virulence factors Correct Answer adhesion and fusion proteins help virus avoid immune recognition, multinucleated giant cells