Pathologie ML3
Inleiding
3 pijlers van de diagnose
1. Anamnese (ziektegeschiedenis)
2. Lichamelijk onderzoek
3. Technische onderzoeken
a. Labo : bloedonderzoek, urine-onderzoek,..
b. Endoscopie
c. ECG
d. EEG (elektro-encefalogram)
e. Longfunctietesten
f. Huidtesten
g. …
Anatomopathologisch onderzoek (APO)
- Cytologisch onderzoek (microscopisch onderzoek van losse cellen)
- Histologisch onderzoek (microscopisch onderzoek van cellen in
weefselverband): biopsie
- Coronair lijden: kransslagaders vernauwd (angina
pectoris)/geblokkeerd (hartinfarct)
- Perifeer vaatlijden: slagader naar been vernauwd
(etalagebenen)
- Cerbrovasculair lijden: geen bloed meer naar
hersenen
- Eerste 2 à 3 uren na onstaan AMI zijn
bepalend
- Hoge sterfte in eerste minuten en uren door
hartritmestoornissen
- Grootte AMI hangt af van duur, afsluiting en
grootte van afgesloten bloedvat
- genetisch en omgevingsfactoren (90%) exogene factoren
- onderliggende ziekten (10%) endogene factoren
o nierziekten
o metabole aandoeningen: hyperthyroide, ziekte van Cushing,
syndroom van Conn
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