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Goede samenvatting van Biochemie 2 - vak in 1x gehaald $6.62   Add to cart

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Goede samenvatting van Biochemie 2 - vak in 1x gehaald

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Deze samenvatting omvat alle hoofdstukken van de powerpoints met eigen notities van alle lessen. Ook staan de belangrijkste figuren en de te kennen structuren er mee in. Met deze samenvatting haalde ik het vak in 1 keer.

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  • August 31, 2023
  • 51
  • 2023/2024
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SAMENVATTING BIOCHEMIE 2
Inhoud
Te kennen structuren............................................................................................................................................................................2
HFST 17. vetzuursynthese.....................................................................................................................................................................4
inleiding.............................................................................................................................................................................................4
voorbereidende fase.........................................................................................................................................................................5
vetzuursynthese................................................................................................................................................................................6
transmembranair transport..............................................................................................................................................................7
regulatie............................................................................................................................................................................................8
HFST. 18 stikstofexcretie.......................................................................................................................................................................8
inleiding.............................................................................................................................................................................................8
verwerking aminogroepen................................................................................................................................................................9
aminozuurafbraak in lever............................................................................................................................................................9
aminozuurafbraak in spierweefsel..............................................................................................................................................10
ureumcyclus....................................................................................................................................................................................11
koppeling ureumcyclus en citroenzuurcyclus.................................................................................................................................12
overzicht transport (transdeaminatie + ureumcyclus)...............................................................................................................12
regulatie..........................................................................................................................................................................................12
verwerking koolstofskelet...............................................................................................................................................................13
biosynthese van aminozuren..........................................................................................................................................................13
HFST. 19 signaaltransductie................................................................................................................................................................14
inleiding...........................................................................................................................................................................................14
ionenkanalen...................................................................................................................................................................................15
receptorenzymen............................................................................................................................................................................15
Insulinereceptor..........................................................................................................................................................................15
Guanylaatcyclase.........................................................................................................................................................................18
receptoren zonder intrinsitke enzymactiviteit...............................................................................................................................18
JAK-stat-mechanisme..................................................................................................................................................................18
G-proteïne-gekoppelde receptoren................................................................................................................................................19
GPKR............................................................................................................................................................................................19
nucleaire receptoren.......................................................................................................................................................................21
zintuigen: zicht................................................................................................................................................................................21
HFST 20. hormonen.............................................................................................................................................................................23
classificatie......................................................................................................................................................................................23
peptidehormonen...........................................................................................................................................................................24
aminozuurderivaten........................................................................................................................................................................24
Schildklierhormonen...................................................................................................................................................................25

1

, eicosanoïden...................................................................................................................................................................................26
prostanoïden...............................................................................................................................................................................26
leukotriënen: lineaire pathway...................................................................................................................................................27
steroïden.........................................................................................................................................................................................27
secosteroïden..................................................................................................................................................................................28
HFST 21: neurotransmitters................................................................................................................................................................28
ionenkanalen...................................................................................................................................................................................28
cholinerge neurotransmissie: acetylcholine...................................................................................................................................30
catecholamines...............................................................................................................................................................................31
andere neurotransmitters...............................................................................................................................................................31
HFSt 22. metabolisme van de lever....................................................................................................................................................32
inleiding...........................................................................................................................................................................................32
koolhydraten...................................................................................................................................................................................32
aminozuren en lipiden....................................................................................................................................................................35
cholesterolmetabolisme.................................................................................................................................................................35
hfst 23. metabolisme van het vetweefsel...........................................................................................................................................38
inleiding...........................................................................................................................................................................................38
glucose-glycerolcyclus.....................................................................................................................................................................39
triacylglycerolcyclus........................................................................................................................................................................40
regulatie..........................................................................................................................................................................................42
hfst 24. globaal metabolisme..............................................................................................................................................................43
spier.................................................................................................................................................................................................43
hersenen..........................................................................................................................................................................................44
pancreas..........................................................................................................................................................................................44
globaal metabolisme.......................................................................................................................................................................45
globaal metabolisme: postprandiaal...............................................................................................................................................46
globaal metabolisme: interprandiaal..............................................................................................................................................47
globaal metabolisme: vasten..........................................................................................................................................................47
regulatie lichaamsmassa.................................................................................................................................................................48




TE KENNEN STRUCTUREN

2

,Structuur Benaming
Glucose




Acetyl-CoA




Malonyl-CoA




Glycerol-3-fosfaat




Glutamaat




3

, Alfa-ketoglutaraat




Glutamine




Ureum




HFST 17. VETZUURSYNTHESE

INLEIDING

- Cellulaire functie van lipiden
o Opslag: triacylglycerolen
o Structurele componenten van membranen
o Gespecialiseerde lipiden (pigmenten, hormonen, …)
- Primaire componenten: vetzuren
- Vetzuursynthese
o Strategie om wateronoplosbare vetzuren te produceren op basis van wateroplosbare precursoren
o Er wordt energie opgeslagen in het vetzuur op een wateroplosbare manier
o β-oxidatie gaat door in mitochondriën
o vetzuursynthese gaat door in het cytosol
o verhouden zich niet tot elkaar zoals glycolyse met gluconeogenese!
- Synthese= opeenvolgend aaneenhechten van 2C-elementen
- Vetzuuroxidatie= opeenvolgend afsplitsen van 2C-elementen
- Nochtans verschillende pathways, enzymen en delen van de cel
- Algemene kenmerken biosynthese van vetzuren
o Endergonsich: kost energie
o Reductief
4

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