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Drug Discovery

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  • Course
  • 115637
  • Institution
  • Singhania University
  • Book
  • Drug Design and Discovery

Drug discovery is the process of identifying and characterizing molecules with the potential to safely modulate disease, with a goal to bring medicines that can improve the lives of patients. It is a lengthy and resource intensive process, that requires close cooperation across multiple disciplines.

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Document information

  • September 2, 2023
  • 46
  • 2023/2024
  • Class notes
  • Hardik
  • All classes

Subjects

  • drug discovery
  • scientist
  • medicine
  • research of drugs
  • clinical research
  • medical part

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  • Singhania University
  • 115637
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Content preview

,• Introduction to Drug Discovery and Design

• Methods of Drug Discovery and Target
validation.

• Combinatorial Chemistry

• Quantitative – Structure Activity and relationship
(QSAR)

• Computer Aided Drug Design (CADD)

,• Drug discovery is the process through which potential new therapeutic entities are identified,
using a combination of computational, experimental, translational, and clinical models

• Drug development and discovery includes preclinical research on cell-based and animal models
and clinical trials on humans, and finally move forward to the step of obtaining regulatory approval
in order to market the drug
• .
• Modern drug discovery involves the identification of screening hits, medicinal chemistry and
optimization of those hits to increase the affinity, selectivity

• Once a compound that fulfills all of these requirements has been identified, it will begin the
process of drug development prior to clinical trials.

o This Special Issue “Drug Design and Discovery: Principles and Applications” was focused on the
basic principles of modern drug design and discovery and the potential applications
o It covered seventeen research articles and one communication contributed from experts all
around the world, as briefed below.

,

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