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Lecture 1: Introduction and Overview – 3rd October 2016
Neurochemistry: Will only be covered at a very basic level.
Main focus: Behavioural effects of psychoactive drugs, a psychological focus.
Clinical drugs: Antipsychotics and antidepressants.
Legal social drugs: Alcohol and Nicotine.
Illicit recreational drugs: Cannabis and MDMA
Historical Introduction and Overview
Human Psychopharmacology: Studying the effects of drugs upon behaviour,
cognitive functions and emotions.
Neolithic times: Opium poppy seeds found in burial chambers. The pain relieving
properties of plants were known a long time before modern day.
Sumeria: Clay tablet laws about drinking alcohol in taverns. Drinking laws in Ancient
Sumeria were similar to that of now in that they had similar problems with alcohol in
terms of disruptive and problematic individuals.
Native Americans: Peyote cactus Contains mescaline which is a psychedelic drug
with similar properties to LSD. It was used in religious ceremonies for religious
insights.
Medieval Europe: Belladonna Pupil dilation using herbs.
1952: Chlorpromazine in France used for schizophrenia.
1960: First benzodiazepine for anxiety reduction. It was widely used but problems
with dependency.
1960Present: Many new drugs for clinical disorders.
The development of which is very complex and expensive.
Nootropic drugs are likely to increase in the future as they are cognitive enhancer which
may be helpful in slowing or stopping the progression of senile dementia. However, the
drug trials show minor effects.
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