Summary
Samenvatting hoofdstuk 1 - deel biochemie - chemie en inleiding tot biochemische processen
- Course
- Institution
Samenvatting van hoofdstuk 1 deel inleiding tot biochemische processen
[Show more]
Seller
Follow
anneleenverhaeghe
Reviews received
Content preview
H1: NIET-COVALENTE KRACHTEN TSS BIOMOLECULENBiochemische processen = essentiële omkeerbare interacties tss biologische moleculen
- Bv. enzym-substraatinteracties, binding vn signaalmol op receptor
- interacties tss functionele groepen vn biomoleculen
o cov bindingen
o vooral zwakke niet-cov aantrekkingskrachten (elektroden delen)
= elektrostatische aantrekkingen (een beetje neg en andere beetje pos)
# types niet-cov krachten (bpld dr polariteit)
- tss geladen / polaire moleculen:
o Ionaire/elektrostatische aantrekking
o Dipoolinteracties (dipool-dipoolkrachten)
o H-bruggen
- tss apolaire moleculen
o Londonkrachten
1.1. IONAIRE AANTREKKING (ZOUTBRUG) & DIPOOL-DIPOOLKRACHT
IONBINDING
= aantrekking tss pos lading (kation) en neg lading (anion)
- dicht genoeg bij mekaar zoutbrug vormen
o belang bij eiwitopvouwing, werking enzymen…
- sterkte: wet van Coulomb: F = (q1 q2) / r² D
o q = grote vn ladingen
o r = afstand tss kation en anion
o D = di-elektriciteits-cte = omgevingsfactoren
(= hoe goed ionen zullen aantrekken, hoe goed zoutbrug kn optreden)
In luchtledige: D=1
In water: D=80
- rel energiesterkte = 33kJ/mol
DIPOOL-DIPOOL-AANTREKKINGSKRACHTEN / KEESOMKRACHTEN
= zwakke aantrekking tss polaire molecule/ functionele groep met partieel pos / neg
lading
- sterkte
o zwakker dn tss ionen
- rechtevenredig met product vn nettodipoolmomenten vn elke molecule
(of vn functionele groepen in biomolecule)
- omgekeerd evenredig met r³
1.2. WATERSTOFBRUGVORMING
- sterkte
o heel zwak in vglm cov bindingen; E = 10^-30 kJ/mol
o ~ positie vn botrokken atomen lineaire H-bruggen = sterkst
- Rol
o Stabilisatie vn structuurelementen in eiwitten
bv. interacties tss complementaire basen vn DNA/RNA
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller anneleenverhaeghe. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.47. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
73314 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now