ATI BOOK-PHARMACOLOGY: UNIT 8: CH 28-29: MEDICATIONS FOR JOINT AND BONE CONDITIONS QUESTIONS AND ANSWERS GRADED
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Ch 28: Connective Tissue Disorders - CORRECT ANSWERS A nurse is reinforcing teaching with a client who has gout and a new prescription for allopurinol. For which of the following adverse effects should the client be taught to monitor? (select all that apply)
A. Stomatitis
B. Insomnia
C. Nausea
D. Rash
E. Increased gout pain - CORRECT ANSWERS 1. Nausea
2. Rash
3. Increased gout pain
*Stomatitis occurs with medications that increase the risk of infection (many of the DMARDs used to treat rheumatoid arthritis). Allopurinol does not increase a client's risk of infection. Insomnia is not an adverse effect caused by allopurinol. Nausea and vomiting are adverse effects that can be caused by allopurinol. Rash and other hypersensitivity reactions can be caused by allopurinol. The client should be taught to contact the provider for any manifestation of hypersensitivity so that the medication can be discontinued. An increase in gout attacks can occur during the first few months in a client who is taking allupurinol.
A nurse is caring for a client who has a new prescription for adalimumab for rheumatoid arthritis. Based on the route of administration of adalimumab, which of the following should the nurse plan to
monitor?
A. The vein for thrombophlebitis during IV administration
B. The subcutaneous site for redness following injection
C. The oral mucosa for ulceration after oral administration
D. The skin for irritation following removal of transdermal patch - CORRECT ANSWERS The subcutaneous site for redness following injection
*Adalimumab is not administered IV. Monitoring for thrombophlebitis during administration is not necessary. Adalimumab is administered subcutaneously, and injection-site redness and swelling are common. It is appropriate to monitor the site for redness following injection. Adalimumab is not ATI BOOK-PHARMACOLOGY: UNIT 8: CH 28-29: MEDICATIONS FOR JOINT AND BONE CONDITIONS QUESTIONS AND ANSWERS GRADED
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administered orally. Monitoring for oral mucosa for ulceration following administration is not necessary. Adalimumab is not administered transdermally. Inspecting the skin for irritation is not necessary.
A nurse is assisting in the plan to administer belimumab for a client who has systemic lupus erythematosus. Which of the following interventions should the nurse recommend to include in the plan?
A. Warm the medication to room temperature over 1 hr before administering
B. Administer the medication by IV bolus over 5 min
C. Dilute the medication in 5% dextrose and water solution
D. Monitor the client for hypersensitivity reactions - CORRECT ANSWERS Monitor the client for hypersensitivity reactions
*The solution of belimumab should be carefully refrigerated and allowed to sit at room temperature for only 10 to 15 min after being taken from the refrigerator. Belimumab is administered by intermittent IV infusion over 1 hr. Belimumab should be diluted only in 0.9% saline solution. Belimumab can cause severe infusion reactions and can cause anaphylaxis. Carefully monitor the client during infusion of this medication and be prepared to slow or stop the medication if a reaction occurs.
A nurse is caring for a client who has a new diagnosis of fibromyalgia. Which of the following medications should the nurse expect to administer to this client?
A. Colchicine
B. Hydroxychloroquine
C. Auranofin
D. Duloxetine - CORRECT ANSWERS Duloxetine
*Colchicine is an anti-inflammatory medication used to treat gout. Hydroxychloroquine is an anti-
malarial medication used as a DMARD along with methotrexate to treat rheumatoid arthritis. Auranofin is a gold salt used to relieve joint pain and stiffness in clients who have rheumatoid arthritis. Duloxetine is a serotonin-norepinephrine reuptake inhibitor used to treat fibromyalgia. Other uses for this medication include treating depression and diabetic peripheral neuropathy.
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