NR 565 Final Exam Advanced Pharmacology Fundamentals Questions and Answers 2023/2024 (A+).

NR 565 Final Exam Advanced Pharmacology Fundamentals Questions and Answers 2023/2024 (A+). NR-565 Advanced Pharmacology Fundamentals NR 565 Final Exam which antacids have the highest absolute neutrophil count (ANC)? - sodium bicarbonate and calcium carbonate What do calcium containing antacids needs for absorption? - vitamin D Antacid Indications - hyperacidity, PUD, GERD, Calcium deficiency, Chronic Renal failure, osteoporosis prevention What is the 1st line therapy for GERD? - H2 blockers and PPIs Antacid ADRs - Mg-diarrhea aluminum & Ca=constipation Antacids: Drug Interactions - Adsorption of other drugs to antacids: Reduces the ability of the other drug to be absorbed into the body=separate administration by 2 hours Distribution of this document is illegal antacid patient education - symptoms > than 2 weeks, extreme pain, cramping, or blood in stool=call provider lifestyle changed to prevent GERD symptoms - stop smoking increase HOB while sleeping no spicy food, no alcohol, no fatty foods, no chocolate, no caffeine Antidiarrheal classes - opiates absorbents anticholinergics Crofelemer Absorbent antidiarrheals drugs - Kaolin pectin Bismuth subsalicylate (Pepto-Bismol) ; use with each loose stool opiate antidiarrheals drugs - Diphenoxylate with atropine (Lomotil) Diphenoxin with atropine (Motofen) Loperamide (immodium) anticholinergic antidiarrheals drugs - atropine propantheline what causes most diarrhea? - infection, food or drug ingestions, or inflammatory bowel disease Distribution of this document is illegal Kaolin MOA - attracts and holds on to bacteria pectin MOA - thickens stool Bismuth Subsalicylate MOA - antisecretory & antimicrobial effects Lomotil (diphenoxylate/atropine) MOA - decreases bowel secretions and peristalsis motofen (difenoxin/atropine) MOA - decreases bowel secretions and peristalsis Loperamide (Imodium) MOA - Decreases GI motility; binds to opioid receptors.