NEU 7: sensory and motor divisions of the nervous sytem
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Course
Neuroscience
Institution
Imperial College London (ICL)
Lecture notes from Imperial College London, Medical Biosciences BSc, 2nd year, Neuroscience (NEU) module.
These notes group both NEU 7a (The Somatosensory System - Chronic Pain) on the sensory system and NEU7b (Motor Control And Parkinson’s Disease) on the motor system.
learning outcomes NE...
- specific receptors sensitive to histamine => itch sensation (urge to scratch)
Sensory transduction & stimulus threshold
, - sensory transduction (name of process):
=> receptors have specific cation channels on the nerve endings: open in response to stimuli
=> to activate mechanoreceptors:
- stretch of the membrane
- force applied to connected extracellular proteins
- force applied to intracellular cytoskeletal components
=> TRP thermoreceptors: sodium & calcium channels activated by changes in temp
- the stimulus intensity needs to reach the threshold to activate the voltage gated Na channels
Stimulus intensity
- firing rate of action potentials correlates to the stimulus intensity:
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