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This course is a prerequisite to BIOC 301: Biochemistry of nucleic acids and
BIOC 307: Antibiotics. It introduces a major group of biomolecules in terms
of their basic constituents and how they are formed. It concerns with the
structures and properties of the 20 amino acids that occur in proteins, amino
acids that are less common but occur in proteins and those amino acids that
do not occur at all in proteins with the levels of protein structure and with
the physico-chemical properties of proteins. In addition the course
introduces the constituents of nucleic acids i.e. the purines and the
pyrimidines and chemical reactions of nucleosides and nucleotides
It is critical that all students of the life sciences know well the structure and
chemistry of the amino acids and other building blocks of biological
molecules. Otherwise, it is impossible to think or talk sensibly about proteins
and enzymes, or the nucleic acids. You are therefore expected to complete
the course in 45 hours within a period of one semester.
The following topics will be addressed:
Topic One The structure of an amino acid and the features that confer
its specific properties
Topic Two Classification of amino acids and their Biological roles
Topic Three Physical and Chemical properties of Proteins
Topic Four Proteins and their structural organization
Topic Five Basic structure of nucleic acids
Topic Six Structural organization of nucleic acids
Topic Seven Physical and Chemical properties of nucleic acids
The course content
The course is broken down into topics. Each topic comprises:
, An introduction to the topic content
New terminology
Core content of the topic
Assignments and/or assessments, as applicable
The unit will be delivered though lectures and related feedback sessions to
ensure students fully understand what is expected of them. Short tests
(formative assessment) will be used throughout the unit to test students'
knowledge and monitor that the right material has been extracted from the
lectures.
Course learning Outcomes
At the end of the course, the students will be expected to:
i. Draw the structure of an amino acid and explain the
features that confer its specific properties.
ii. Classify amino acids and outline their Biological roles
Learning iii. Explain the structural organization of proteins
Outcomes
iv. Understand the physical and chemical properties of
proteins
v. Draw the basic structure of nucleic acids
vi. Understand the physical and chemical properties of nucleic acids
Course Study Skills
All students undertaking this course in biochemistry and molecular biology
should acquire a sound understanding of Biochemistry as well as:
Become intellectually independent learners
Recognize and confront areas of personal ignorance
Review and apply chemical, biological, physical and mathematical
principles in a biochemical context
Improve problem-solving skills
, Create, understand and value abstract biochemical models
See biochemistry in relevant historical and societal contexts
Discover and use the resources of the library and the Internet
Gain confidence in reading and understanding scientific articles
Appreciate importance of clear oral and written communication
For this class, as a group, to become sufficiently skilled learners to score
significantly well as they lay the foundation of the four years journey. In
order for this to happen, you will need to work individually and together so
that everyone learns. Everyone here has unique and special abilities,
background and personality to contribute to the effort.
Course Assignments/Activities
Two assignments will be given. The assignments will be
online or orally presented as a group activity on campus.
They will be given at the beginning of suitable topics and
Assignment
submitted in 2 weeks‘ time. The assignment will make 5%
of the course.
Assessments
The course will comprise 2 continuous assessment tests
marked out of 30 and converted to 25%. The main Exam
will be marked out of 70. The CAT will be done during the
Assessment
5th and 9th week of the semester. The assessments will be a
1 hour teacher-marked test. More communication on online assessment in
the course of the semester as we deal with the pandemic.
Self-assessment
Self-assessments are provided in order to aid your understanding of the
topic and course content. While they may not be graded, you are strongly
advised to attempt them whenever they are available in a topic.
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