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NSG 6005 MIDTERM EXAM 2 VERSIONS .
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NSG 6005 MIDTERM EXAM2 VERSIONS
2023/2024
,1) A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to
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prescribing because: Distribution of drugs to target tissue may be affected.
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2) Drugs that have a significant first-pass effect: Are rapidly metabolized by the liver and
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may have little if any desired action.
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3) The route of excretion of a volatile drug will likely be: The lungs
4) The point in time on the drug concentration curve that indicates the first sign of a
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therapeutic effect is the: Onset of action
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5) Factors that affect gastric drug absorption include: Lipid solubility of the drug
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6) Which one of the following statements about bioavailability is true? Bioavailability
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issues are especially important for drugs with narrow therapeutic ranges or sustained
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release mechanisms.
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7) Steady state is: When the amount of drug in the body remains constant.
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8) The time required for the amount of drug in the body to decrease by 50% is called: Half-
life
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9) An advantage of prescribing a sublingual medication is that the medication is: Absorbed
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rapidly
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10) Drugs that use CYP3A4 isoenzymes for metabolism may: Both A and B(Induce the
metabolism of another drug; inhibit the metabolism of another drug)
,11) A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old
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because: A six-year-old may have problems swallowing a pill
12) The first step in the prescribing process according to the World Health Organization is:
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Diagnosing the patient’s problem
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13) Patient education regarding prescribed medication includes: Discussion of expected
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ADRs
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14) Pharmacokinetic factors that affect prescribing include: Bioavailability
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15) Infants and young children are at higher risk of ADRs due to: Lack of safety and efficacy
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studies in the pediatric population.
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16) Infants and young children are at higher risk of ADRs due to: Lack of safety and efficacy
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studies in the pediatric population.
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17) The elderly are at high risk of ADRs due to: Age-related decrease in renal-function
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18) The type of ADR that is the result of an unwanted but otherwise normal pharmacological
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action of a drug given in the usual therapeutic doses is: Type A
19) A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia
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is: A cytoxic hypersensitivity reaction
20) The angiotensin converting enzyme (ACE) inhibitor Lisinopril is a known teratogen.
Teratogens cause Type ADR. D
21) A twenty-four-year-old male received multiple fractures in a motor vehicle accident that
required significant amounts of opioid medication to treat his pain. He is at risk for Type
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ADR when he no longer requires the opioids. E
22) Which of the following factors may adversely affect a patient’s adherence to a therapeutic
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drug regimen? Both A and B
, 23) Nonadherence is especially common in drugs that treat asymptomatic conditions, such as
hypertension. One way to reduce the likelihood of nonadherence to these drugs is to
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prescribe a drug that: Has a tolerability profile with less of the adverse effects that are
considered “irritating,” such as nausea and dizziness
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24) Patients with psychiatric illnesses have adherence rates to their drug regimen between
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35% and 60%. To improve adherence in this population, prescribe drugs: With a longer
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half-life so that missed doses produce a longer taper on the drug curve
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25) Genetic polymorphisms account for differences in metabolism, including: All of the
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above (Poor metabolizers (PMs) that lack a working enzyme; Intermediate metabolizers
(IMs) that have on working, wild-type allele and one mutant allele; Extensive
metabolizers (EMs), with two normally functioning alleles)
26) Warfarin resistance may be seen in patients with VCORC1 mutation, leading to:
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Decreased response to warfarin
27) Genetic testing for VCORC1 mutation to assess potential warfarin resistance is required
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prior to prescribing warfarin. False
28) Carbamazepine has a black box warning recommending testing for the HLA-B*1502
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allele in patients with Asian ancestry prior to starting therapy due to: Increased risk for
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Stevens-Johnson syndrome in Asian patients with HLAB*1502 allele
29) Herbs and supplements are tested for safety by the FDA. False
30) Carbamazepine has a black box warning recommending testing for the HLA-B*1502
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allele in patients with Asian ancestry prior to starting therapy due to: Increased risk for
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Stevens-Johnson syndrome in Asian patients with HLAB*1502 allele
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