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LIPOGÉNESIS LIPÓLISIS Y BETAOXIDACION $6.49   Add to cart

Class notes

LIPOGÉNESIS LIPÓLISIS Y BETAOXIDACION

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Se describe en esquemas la lipogénesis lipólisis y betaoxidación

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  • October 15, 2023
  • 6
  • 2023/2024
  • Class notes
  • Dra. villanela
  • All classes
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APUNTES DE
BIOQUIMICA
METABOLISMO DE
LIPIDOS (Acidos grasos y
trigliceridos)

, METABOLISMO DE
ACIDOS GRASOS
SINTESIS/LIPOGENESIS BREAKDOWN/BETA OXIDACION


Principal meta Formar acidos grasos Generar energia


Sitio Citoplasma Mitocondria


Hígado y tejido adiposo

Tejido musculo y otros tejidos
glandulas mamarias (Almacena
NO: cerebro que no usa lipidos, GR NO
en adipocitos)
tiene mitocondria


Precursor Acetil CoA Acyl Coa


Transportador Lanzadera de citrato Lanzadera de carnitina


Enzima que
Carnitina palmiotiltransferasa I /
determina la Acetil CoA carboxilasa
carnitina acyltransferasa I
velocidad


ATP
NAD+
Sustancias Biotina cofactor
FAD
requeridas CO2
H2O
NADPH


INSULINA
hiperglicemia
Regulacion ATP
glucagon indirectamente
positiva Estados de alta energia: ATP y
NADPH INH a la isocitrato
dehidrogenasa: +++ Citrato


glucagon hipoglicemia epinefrina Malonyl CoA (intermediario de
Regulacion
AMP y catecolaminas lipogenesis INH CAT I)
negativa
AcylCoA y palmitoil CoA Insulina (indirecto)


Acetil CoA
Productos Acido palmitico cuerpos cetonicos
finales NADP NADH+
FADH2

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