Samenvatting H2 "Bioinformatic and Functional Genomics"
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Course
Theorie van BioInformatica 1
Institution
Hanzehogeschool Groningen (Hanze)
Book
Bioinformatics and Functional Genomics
Samenvatting H2 "Bioinformatic and Functional Genomics", dit hoofdstuk gaat over online databases en hoe je aan sequence data kan komen in die databases.
Samenvatting H1 "Bioinformatic and Functional Genomics"
Samenvatting H3 "Bioinformatic and Functional Genomics"
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Hanzehogeschool Groningen (Hanze)
Bio-informatica
Theorie van BioInformatica 1
All documents for this subject (5)
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Content preview
Hoofdstuk 2: access genomes
➢ What is bioinformatics?
♥ Interface of biology and computers
♥ Analysis of proteins, genes and genomes using computer algorithms and computer databases
♥ The tools of bioinformatics are used to make sense of the billions of base pairs of DNA that are sequenced
by genomics projects.
♪ Genomics is the analysis of genomes.
♥ Three perspectives on bioinformatics
♪ The cell
❖
❖
❖ Arrival of next-generation sequencing:
• We have sequenced hundreds of terabases (November 2012)
• 6 years ago GenBank celebrated reaching 100 billion base pairs of DNA.
• Now when my lab sequences the genome of one patient, we obtain ~150 billion base pairs of
sequence and ~1 terabyte of data for $3,000.
• This course will reflect the major impact of increased DNA sequencing on all areas of biology.
♪ The organism
❖
♪ The tree of life
❖
➢ NCBI
♥ NCBI key features
♪ PubMed
❖ National Library of Medicine's search service
❖ 22 million citations in MEDLINE (as of 2012)
❖ links to participating online journals
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