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Samenvatting H2 "Bioinformatic and Functional Genomics" $7.04   Add to cart

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Samenvatting H2 "Bioinformatic and Functional Genomics"

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Samenvatting H2 "Bioinformatic and Functional Genomics", dit hoofdstuk gaat over online databases en hoe je aan sequence data kan komen in die databases.

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  • No
  • H2
  • October 27, 2017
  • 2
  • 2017/2018
  • Summary
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Hoofdstuk 2: access genomes

➢ What is bioinformatics?
♥ Interface of biology and computers
♥ Analysis of proteins, genes and genomes using computer algorithms and computer databases
♥ The tools of bioinformatics are used to make sense of the billions of base pairs of DNA that are sequenced
by genomics projects.
♪ Genomics is the analysis of genomes.
♥ Three perspectives on bioinformatics
♪ The cell










❖ Arrival of next-generation sequencing:
• We have sequenced hundreds of terabases (November 2012)
• 6 years ago GenBank celebrated reaching 100 billion base pairs of DNA.
• Now when my lab sequences the genome of one patient, we obtain ~150 billion base pairs of
sequence and ~1 terabyte of data for $3,000.
• This course will reflect the major impact of increased DNA sequencing on all areas of biology.

♪ The organism





♪ The tree of life





➢ NCBI
♥ NCBI key features
♪ PubMed
❖ National Library of Medicine's search service
❖ 22 million citations in MEDLINE (as of 2012)
❖ links to participating online journals

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