100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Samenvatting Immunologie $4.82   Add to cart
Quickly navigate to
Preview
  2.  
  3. Artesis Plantijn Hogeschool Antwerpen (Artesis)
  4.  
  5. Biomedische Laboratoriumtechnologie
  6.  
  7. Hematologie 1

Summary

Samenvatting Immunologie
 10 views  0 purchase
  • Course
  • Hematologie 1
  • Institution
  • Artesis Plantijn Hogeschool Antwerpen (Artesis)

Samenvatting deel immunologie uit Hematologie 1 AP hogeschool Antwerpen

Preview 3 out of 21  pages

Document information

  • October 19, 2023
  • 21
  • 2022/2023
  • Summary

Subjects

  • immunologie
  • hematologie 1
  • ap
  • biomedische laboratoriumtechnieken

Written for

  • Artesis Plantijn Hogeschool Antwerpen (Artesis)
  • Biomedische Laboratoriumtechnologie
  • Hematologie 1
All documents for this subject (15)

Seller

avatar-seller
nettemoons

Reviews received

Content preview

IMMUNOLOGIE Nette Moons
2022 - 2023

LECTOR PITTOIS KAREN

,INHOUDSOPGAVEN

1. Inleiding ............................................................................................................................................................... 2

1.1 Onderscheid tussen eigen en niet-eigen ....................................................................................................... 2

1.2 De pathogenen .............................................................................................................................................. 3

1.3 Plaats van het verweer .................................................................................................................................. 3

1.4 Enkele begrippen........................................................................................................................................... 4

2. Het niet-specifiek verweer .................................................................................................................................. 6

2.1 Barrières van het niet-specifieke verweer .................................................................................................... 6

2.2 De cellen van het niet-specifiek verweer: ..................................................................................................... 7

2.3 Cellulaire mechanismen: ............................................................................................................................... 7

2.4 Onderscheid tussen eigen en niet-eigen: receptoren ................................................................................... 9

2.5 De eiwitten van het niet-specifiek verweer: ................................................................................................. 9

3. Het specifiek verweer: antigenen ..................................................................................................................... 12

3.1 Inleiding: fronten, vergelijking specifiek/niet-specifiek verweer ................................................................ 12

3.2 Antigenen .................................................................................................................................................... 12

4. Het specifiek verweer: antilichamen ................................................................................................................. 16

4.1 Structuur ..................................................................................................................................................... 16

4.2 Isotypes ....................................................................................................................................................... 17

4.3 Biologische functies ..................................................................................................................................... 18

4.4 Antigeen-antilichaaminteractie................................................................................................................... 18

4.5 Werking antilichamen ................................................................................................................................. 19

Lesdoelen .............................................................................................................................................................. 20

1. Inleiding ......................................................................................................................................................... 20

2. Het niet-specifiek verweer ............................................................................................................................ 20

3. Het specifiek verweer: antigenen ................................................................................................................. 20

4. Het specifiek verweer: antilichamen ............................................................................................................. 20




1

, 1. INLEIDING

Het verweer
• Voorkomt invasie van vreemde organismen en moleculen → bescherming tegen ziekte
• Balans tussen vernietigen vreemde cellen en vermijden van zelfdestructie
→ Onderscheid tussen eigen en niet-eigen
→ Afwijkingen
o Immuundeficiëntie : verzwakt immuunsysteem (Vb. AIDS)
o Hypergevoeligheid : overactief (allergie)
o Auto-immuniteit : reactie tegen eigen lichaamscellen
• Spreken over 2 soorten verweer
o Niet-specifiek verweer = aangeboren = innate immune system
o Specifiek verweer = verworven = adaptive immune system



1.1 ONDERSCHEID TUSSEN EIGEN EN NIET -EIGEN

Niet-eigen = indringers zoals bacteriën, abnormale lichaamscellen (kanker),…

Niet-specifiek Specifiek
• Bestaande, aangeboren componenten • Verworven
• Snelle respons: min. • Respons: dagen
• Niet-specifiek: zelfde moleculen voor hele • Zeer specifiek: cellen zijn genetisch
reeks pathogenen geprogrammeerd om te reageren op één
• Algemene receptoren: ‘pattern-recognition’ antigeen
moleculen • AG herkennende moleculen
• Geen geheugen • Geheugen
• Weinig afwijkingen • Frequent afwijkingen: auto-immuniteit,
immuundeficiëntie

Receptoren
Het immuunsysteem beschikt over receptoren die tijdens de ontwikkeling ‘leren’ welke eigen en niet-eigen zijn

Receptor/ligand interactie = algemeen biochemisch verschijnsel → manier van communicatie / geeft reactie

[L][R]
Kd = [LR]
= bindings- of associatieconstante → indien klein = grote affiniteit tussen ligand en receptor




2

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller nettemoons. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $4.82. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

72042 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$4.82
  • (0)
  Add to cart