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Samenvatting Labcluster Klinische biologie 2 - Hematologie

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Labcluster Klinische Biologie 2

Institution
Artesis Plantijn Hogeschool Antwerpen (Artesis)

Samenvatting van lab hematologie uit het vak labcluster klinische biologie 2 () Samenvatting van de cursus lab hematologie + notities gemaakt tijdens het labo

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Uploaded on October 25, 2023
Number of pages 24
Written in 2023/2024
Type Summary

lab klinische biologie
klinische biologie 2
hematologie
lab hematologie 2
labcluster klinische biologie 2
ap
medische laboratoriumtechnieken

Institution
Artesis Plantijn Hogeschool Antwerpen (Artesis)
Education
Medische Laboratoriumtechnologie
Course
Labcluster Klinische Biologie 2

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LAB KLINISCHE BIOLOGIE 2
Lector. Appels Ann

2023 - 2024

,INHOUD

1. Bloedafnamens ................................................................................................................................................... 3

1.1 Veneuze bloedafnamen ................................................................................................................................ 3

1.1.1 Benodigdheden ...................................................................................................................................... 3

1.1.2 Afnamevolgorde ..................................................................................................................................... 3

1.1.3 Voorbereiding ........................................................................................................................................ 3

1.1.4 Uitvoering ............................................................................................................................................... 4

1.1.5 Naalden voor bloedafnamen ................................................................................................................. 4

1.1.6 Problemen bij bloedafnamen ................................................................................................................. 4

1.2 Capillaire bloedafnamen ............................................................................................................................... 5

1.3 Bloedafnamen via een IV katheter ................................................................................................................ 5

1.4 Rol van bloedafname in het hele proces van het bloedonderzoek ............................................................... 5

1.5 LAB ................................................................................................................................................................ 5

2. Hemostase .......................................................................................................................................................... 6

2.1 Inleiding ......................................................................................................................................................... 6

2.2 Vasculaire fase .............................................................................................................................................. 7

2.3 Primaire hemostase (bloedplaatjes fase) ...................................................................................................... 7

2.3.1 Bloedingstijd ........................................................................................................................................... 8

2.3.2 Trombocytentelling ................................................................................................................................ 8

2.4 Secundaire hemostase .................................................................................................................................. 8

2.4.1 Aandachtspunten en doel bij stollingstesten ......................................................................................... 8

2.5 LAB ................................................................................................................................................................ 9

2.5.1 Meetprincipe .......................................................................................................................................... 9

2.5.2 APTT = geactiveerde partiële tromboplastinetijd .................................................................................. 9

2.5.3 PTT = Protrombinetijd .......................................................................................................................... 10

2.5.4 Fibrinogeen .......................................................................................................................................... 10

2.6 Uitbreiding : laboratoriumonderzoek bij trombose .................................................................................... 10

1

, 3. Cytologie ........................................................................................................................................................... 11

3.1 Leukocyten .................................................................................................................................................. 12

3.1.1 Afwijkingen in het cytoplasma van granulocyten ................................................................................ 13

3.1.2 Kernafwijkingen van granulocyten ....................................................................................................... 13

3.1.3 Afwijkingen van lymfocyten ................................................................................................................. 13

3.1.4 Maligne lymfomen ............................................................................................................................... 13

3.2 Erytrocyten .................................................................................................................................................. 14

3.2.1 Afwijkingen ........................................................................................................................................... 14

3.3 Trombocyten ............................................................................................................................................... 16

3.3.1 Afwijkingen ........................................................................................................................................... 16

3.3.2 Atrefacten ............................................................................................................................................ 16

3.4 referentiewaarden hematologie ................................................................................................................. 17

4. Immuunhematologie ......................................................................................................................................... 18

4.1 Bloedgroepen .............................................................................................................................................. 18

4.1.1 Basisbegrippen ..................................................................................................................................... 18

4.1.2 Bloedgroep antistoffen ........................................................................................................................ 18

4.1.3 Klinisch belang ...................................................................................................................................... 18

4.1.4 Bloedgroepensystemen ....................................................................................................................... 19

4.2 Lab ............................................................................................................................................................... 20

4.2.1 in de practijk ......................................................................................................................................... 20

4.2.2 Problemen bij de bloedgroepbepaling ................................................................................................. 20

4.2.3 ABO-bloedgroepbepaling en rhesus-fenotypering .............................................................................. 20

4.3 Bloedgroepantistoffen ................................................................................................................................ 21

4.3.1 Antiglobuline test ................................................................................................................................. 22

4.4 Zwangerschap en geboorte ......................................................................................................................... 22

4.4.1 Hemolytische ziekte van de pasgeborene ............................................................................................ 22

4.4.2 Foetale cellen ....................................................................................................................................... 22

4.4.3 Rhesus-D-antagonisme ........................................................................................................................ 23

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