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ONS Chemotherapy Immunotherapy Certificate Exam 2025 Questions and Answers 2025 / 2026 (Verified Answers)
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ONS Chemotherapy Immunotherapy Certificate Exam 2025 Questions and Answers 2025 / 2026 (Verified Answers)

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  • October 31, 2023
  • 34
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

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  • ons
  • ons chemotherapy immunotherapy certificate
  • chemotherapy immunotherapy certificate exam
  • ons chemotherapy immunotherapy certificate exam

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ONS Chemotherapy Immunotherapy Certificate

1. 3 major phases of cell division::

Interphase Mitotic phase

Cytokinesis

2. 3 steps of interphase:: First growth phase

(G1) Synthesis phase (S phase)

Second growth phase (G2)

3. 4 phases of mitosis::

Prophase Metaphase

Anaphas

e

Telophas

e

4. Innate immunity:: Non-specific response, either:

1. Barrier (skin, mucous membranes, flora of skin/gut)

2. Cellular components (phagocytes, natural killer cells,

granulocytes, macrophages)

5. Adaptive immunity:: Follows innate immunity if unsuccessful. Memory

immunity, including:


,1. Humoral immunity (production of antibodies or immunoglobulins)

2. Cell mediated immunity (dependent upon T cells)

3. Regulatory T -cells (prevent autoimmune reactions and limit

inflammatory re- sponses)

6. Define mutations: Variations in the nucleotide sequence of a gene

7. 3 main goals of treatment::

Cure Control

Palliation

8. Define neoadjuvant therapy: Treatment is given prior to surgery to

shrink the tumor

9. Define adjuvant therapy: Additional cancer treatment given after the

primary treatment to lower the risk that the cancer reoccur

10.Define conditioning/preparative therapy: Treatments used to prepare

a pa- tient for stem cell transplantation

11.2 types of conditioning therapies::

Myeloablative Nonmyeloablative

12.Define dose density: Drug dose per unit of time

13.Define dose intensity: Amount of drug delivered over time

14.How is relative dose intensity (RDI) calculated?: By comparing the dose


,that the patient ACTUALLY received to the planned dose of the standard

regimen

15.How do alkylating agents work?: By causing a break in the DNA helix

strand, interfering with DNA replication and causing cell death






, 16.3 subcategories of alkylating agents:: 1. Nitrogen mustards

2. Platinum-based agents (do not possess an alkyl group but still termed

alkylating agents as they work similarly)

3. Nitrosoureas

17.Most common subcategory of alkylating agents:: Nitrogen mustards

18.Common alkylating agents:: Cyclophosphamide

(Cytoxan) Ifosfamide (Ifex)

Bendamustine (Treanda)

19.Common platinum-based agents:: Cisplatin

(Platinol) Carboplatin (Paraplatin)

20.What is unique about nitrosoureas agents?: Able to cross the blood-

brain barrier; can be effective in treating some brain tumors

21.Common nitrosoureas agents:: Carmustine

(BiCNU) Lomustine (CeeNu)

Streptozocin (Zanosar)

22.Hypersensitivity can occur with late doses of:: Carboplatin

23.These agents are typically categorized as highly emetogenic:: 1.

Alkylating agents

2. Nitrosoureas

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