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Samenvatting Samenvattende schema's infectieziekten 2 $8.04   Add to cart

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Samenvatting Samenvattende schema's infectieziekten 2

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Deze schema's vatten overzichtelijk alle antibiotica, bacteriën, virussen, vaccins en parasieten samen van infectieziekten 2 aan de Universiteit Antwerpen. Doorheen de lessen is het soms moeilijk om het bos tussen de bomen te zien, dus dit is het perfecte overzicht om alles in je geheugen te kunne...

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  • November 3, 2023
  • 16
  • 2022/2023
  • Summary

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By: adventureaforet • 10 months ago

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Samenvattende schema’s infectieziekten 2
Antibiotica, bacteriën, virussen, vaccins, parasieten




1

, Antibiotica
Klasse Werking Voorbeeld Info
Bèta lactam
Penicillines Celwand stuk door binding op PBP Penicilline Gram+, streptokokken, syfilis
(peniciline binding protein) Cloxacilline Gram+, staphylococcus (MSSA),
Beste keuze invasieve S. aureus
infecties bv. abcessen
Amoxicilline + clavulaanzuur Gram+-, anaeroben, bypass bèta-
lactamases
Carbapenems Ongevoelig voor sommige beta- Mereponem Gram+-, anaeroben, ESBL,
lactamases pseudomonas, breed-spectrum
Cephalosporines Ceftriaxone (3de generatie) Gram+-, meningitis, link met ESBL


Non-bèta lactam
Aminoglycosides Blokkage van eiwitsynthese op Gentamicine Gram(+)-, niche: moeilijke gram+,
andere manier dan macroliden, geen stand-alone, veel resistentie,
nefro- en ototoxiciteit! bloedbaaninfecties
Amikacine Gram(+)-, bloedbaaninfecties, co-
resistentie ESBL, peak MIC
Fluoroquinolones Open en toe gaan van circulair DNA ciprofloxacine Gram(+)-, intracellulair, salmonella,
wordt verhinderd 2nd line tbc, snel resistentie in
monotherapie, Link met selectie
ESBL (co-resis.)
Enrofloxacine Diergeneeskunde, landbouw →
resistentie
Sulfonamides Co-trimoxazole: nucleïnezuur Co-trimoxazole Gram+-, nevenwerkingen en
sabotage door verstoring resistentie → in onbruik, goede
foliumzuurmetabolisme penetratie in weefsels
Glycopeptides Inhibitor celwandsynthese Vancomycine Gram+, MRSA, ampi-resistente
enterococci, renale toxiciteit →
bloed level monitoring

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