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Behaviour of molecules Lecture notes: Nucleophilic Substitution
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BSc Biomedical Sciences Behaviour of molecules Lecture notes: Nucleophilic Substitution
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BIOL1021: Behaviour of BiomoleculesDr. Ramon Rios: rrt1f11@soton.ac.uk
Behaviour of Biomolecules
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Lecture 1: Nucleophilic Substitution
,BIOL1021: Behaviour of Biomolecules
What’s the purpose of these modules?
• BIOL1021 Modules A & B aim to provide you with the necessary chemistry
background for your future biological science studies.
• Overview of important mechanisms that play a role in biological chemistry
• Emphasis upon understanding how these reactions take place (curly
arrows!)
• Biological processes will be given as examples to illustrate the relevance of
the chemistry to your biological science studies.
How will you be expected to show your understanding of these
reactions?
• From a set of given starting materials and a product, you will be expected
to draw the curly arrow mechanism, including intermediate structures.
• From a set of given starting materials and reagents, you will be expected to
be able to draw the product which will be formed.
2
, Organisation
•For each lecture there is a worksheet which contains a set of problems to
illustrate the principles of the lecture material.
•The workshop will contain exam-style questions and will be online
•Extra Exercises will be placed in Blackboard and you can send it to me. They will
be corrected and feedback will be given. .
•On Blackboard:
•Worksheet Q & A sheets.
•Workshop Q & A sheets.
•A copy of the lecture handouts.
•Additional self-study material taken from Organic Chemistry by Clayden,
Greeves & Warren (2nd Ed. OUP, 2012, ISBN: ISBN: 978-0199270293).
•A type past exam questions
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