NURS 5334 Adv. Pharmacotherapeutics, Final Exam Review With 100% Correct Answers 2023
Why do many medications lack pediatric dosing information in their drug labeling?
A. Most medications are not used in pediatric patients. B. There is a lack of evidence-based literature on the safe and effective use of medications in children.
C. The FDA does not allow pediatric dosing information in product labeling. D. Only products available as oral liquid formulations are required to contain pediatric dosing information in their labeling. - Correct Answer-B. There is a lack of evidence-
based literature on the safe and effective use of medications in children.
Why are Neonates at greater risk for toxicity with highly protein-bound drugs? A. Protein binding is decreased in neonates increasing the amount of free drug available. B. The protein-bound drugs are not eliminated effectively in neonates. C. Neonates are unable to metabolize these highly protein-bound drugs. D. Protein binding is increased in neonates, making measurement of serum levels of the
drug inaccurate. - Correct Answer-A. Protein binding is decreased in neonates increasing the amount of free drug available.
At what age are adult levels of renal function achieved? •
A. 6 months B. 12 months C. 24 months D. 3 years old - Correct Answer-B. 12 months
What is the list that identifies drugs with a high likelihood of causing adverse effects in the elderly? A. No use list B. Beers list C. Pharmacists list D. Adverse drug list - Correct Answer-B. Beers list
In pediatric patients gastric acidity does not reach adult values for ______ - Correct Answer-2 Years
The principles underlying complication to drug therapy in the elderly include___, ____, ____, and ____. - Correct Answer-altered pharmacokinetics, multiple and severe illnesses, multiple-drug therapy, and poor adherence. Altered absorption of drugs in the elderly may result in____drug response - Correct Answer-Delay
The four major factors that can alter drug distribution in the elderly include _, _, _, and _? - Correct Answer-increased body fat, decreased percentage of lean body mass, decreased total body water, and reduced concentration of serum albumin.
The most important cause of adverse drug reactions in the elderly is___. - Correct Answer-drug accumulation secondary to reduced renal excretion.
In the elderly, the proper index of renal function is____. - Correct Answer-creatinine clearance or GFR
Name factors underlying the increase in adverse reactions in the geriatric population: - Correct Answer-• Polypharmacy • Severe illness, • multiple pathologies, • greater use of drugs that have a low therapeutic index
• Inadequate supervision • Poor patient adherence
What is maximum amount of Sumatriptan that can be taken in 1 day? A. 100 mg B. 200 mg C. 300 mg D. 400 mg - Correct Answer-B. 200 mg
The ability of the anesthetic to penetrate the axon membrane is determined by 3 properties. What are they? A. Molecular size B. Protein binding potential C. Lipid solubility D. Degree of ionization at tissue pH E. Water solubility F. Degree of blood flow - Correct Answer-A. Molecular size C. Lipid solubility D. Degree of ionization at tissue pH
Which of the following medications will not cause rebound headaches from overuse? A. Propranolol B. Sumatriptan C. Acetaminophen
D. Ibuprofen - Correct Answer-A. Propranolol
Which of the following is best option for menstrual migraine? A. Sumatriptan at onset
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