sclerosis (MS) Questions With Complete
Solutions
an inflammatory disease of the central nervous system with an
unknown etiology correct answer: multiple sclerosis (MS)
when myelin sheaths in multiple areas of the brain and spinal
cord are damaged correct answer: demyelination
scar tissue (plaque) formed correct answer: sclerosis
causes of MS correct answer: immunologic
genetic
environmental
infections
prevalence worldwide correct answer: > 2.3 million
prevalence in the US correct answer: ~400,000 people
__% of diagnosed cases are women correct answer: 60%
MS is more common in the... (geographical) correct answer:
northern US and canada
MS is more common in... (nationality) correct answer: whites of
northern european descent
, ___% disabled within 10 years of diagnosis correct answer:
>50%
lifetime costs correct answer: > $1 million per person
etiology is correct answer: not known
pathophysiology correct answer: autoimmune disease
destruction of oligodentrites and myelin sheath
plaque formation
disruption of nerve impulse
disability
autoreactive T-cells enter the CNS and... correct answer: secrete
lymmphokines or cytokines that recruit cells that participate in
demylination
symptoms correct answer: fatigue, numbness, walking, balance
& coordination problems, bladder dysfunction, bowel
dysfunction, vision problems, dizziness & vertigo, sexual
dysfunction, spasticity, pain, cognitive impairment, emotional
changes, depression
less common symptoms correct answer: speech disorders,
swallowing problems, headache, hearing loss, seizures, tremor,
breathing problems, itching
overwhelming tiredness (often a major consideration) correct
answer: fatigue