CPHON exam 2023 with 100% correct answers

Thalassemia - correct answer Inherited defect in production of hemoglobin chain. Destruction of RBC. Treatment: frequent RBC transfusions Sickle Cell Disease - correct answer inherited defect of hemoglobin causing sickling. destruction of RBC hemophilia - correct answer Congenital deficiency in clotting factor. prolonged bleeding. von Willebrand Disease (vWB) - correct answer inherited deficiency or defective clotting protein. mucous membrane bleeding Immune Thrombocytopenia (ITP) - correct answer ACQUIRED. disorder of excessive platelet destruction Aplastic Anemia - correct answer suppression of production of formed elements in blood. Congenital or acquired. Red Cell Aplasia - correct answer lack of erythoid cell. Congential = Diamond blackfan. Can be acquired What does mutatin result in? - correct answer 1. lack of differentiation 2. loss of contact inhibition 3. unregulated growth 4. cellular immortality what are genetic predispositions to cancer? - correct answer 1. down syndrome 2. Li-Fraumeni