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UNIT 2 BIOCHEMISTRY TEST- UNE QUESTIONS WITH 100% CORRECT ANSWERS.
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UNIT 2 BIOCHEMISTRY TEST- UNEQUESTIONS WITH 100% CORRECT
ANSWERS
Cortisol is a steroid hormone that increases protein catabolism from skeletal muscle. It does this
through which of the following mechanisms? - answer Transcriptional regulation
Pyruvate dehydrogenase complex is highly regulated. The enzyme will be most active when
which of the following compounds is high? - answer Pyruvate
α-ketoglutarate dehydrogenase is the enzyme responsible for one of the irreversible reactions in
the TCA cycle. The enzyme catalyzes which of the following conversions? - answer α -
ketoglutarate to succinyl CoA
A deficiency in thiamine can reduce the activity of the pyruvate dehydrogenase complex. Under
these conditions, might you expect to have a higher than normal blood concentration of which
of the following metabolites? - answer Pyruvate
Which of the following is an inhibitor of isocitrate dehydrogenase, and α-ketoglutarate
dehydrogenase? - answer NADH
What sequence of enzymes allows for the synthesis of glycogen from glucose-6-phosphate? -
answer phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, amylo-
(1,4α1,6)-transglycosylase
Which oxidation reaction requires the coenzyme FAD because it involves oxidation of a carbon-
carbon single bond to a double bond? - answer Oxidation of succincate to fumerate
TCA cycle intermediates are always being removed for various metabolic processes. One
example of this is the removal of succinyl CoA which is used for the synthesis of which of the
following compounds? - answer Heme
, Which of the following hormones increases the production of cAMP? - answer Glucagon
Individuals with deficiency in glucose 6 phosphate dehydrogenase often present with hemolytic
anemia. This is primarily due to a deficiency in which of the following metabolic products? -
answer NADPH
In the malate aspartate shuttle, glutamate is converted to _________ in the mitochondria while
aspartate is converted to ___________ in the cytosol. - answer α-ketoglutarate; oxaloacetate
The order of prosthetic groups as they act in the three proteins of the PDC(pyruvate
dehydrogenase complex)is: - answer thiamine pyrophosphate → lipoate → FAD
Heat can be generated in the brown adipose tissue of hibernating mammals due to which of the
following processes? - answer Uncoupling of the electron transport chain by thermogenin
Under low energy conditions, AMP will bind to phosphofructokinase I and glycogen
phosphorylase. This is an example of which of the follow types of enzyme regulation? - answer
allosteric activation
The Cori cycle describes the movement of lactate from the red blood cell to the liver. Within the
liver, the lactate is primarily used as a substrate for which of the following metabolic processes?
- answer Gluconeogenesis
What is the primary oxidized fuel in skeletal muscle in the fasted state? - answer Free Fatty
Acids
Pyruvate dehydrogenase kinase will facilitate which of the following reactions? - answer The
pyruvate dehydrogenase kinse will phosphorylate and inactivate the pyruvate dehydrogenase
complex.
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