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BMTCN - CHAPTER 6 WITH COMPLETE SOLUTIONS ALREADY GRADED A+
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BMTCN - CHAPTER 6 WITH COMPLETE SOLUTIONS ALREADY GRADED A+
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BMTCN NUMBERS TO KNOWLeukapheresis
- Peripheral blood stem cell collection: goal # cells in adults vs. pediatrics, how much blood
commonly processed
- Bone marrow: goal # cells, how much marrow obtained - answer PBSCs: 5 x10^6 CD34+ cells
per kg of recipient's body weight
- Adults: 12-15L of blood commonly processed
- Pediatrics: 200-250 mL/kg of blood commonly processed
**If < 25kg, will require a blood prime to offset anemia
Bone marrow: 2-3 x 10^8 nucleated cells per kg of recipient's body weight
- 1-2 L marrow volume usually obtained
Harvest volumes - answer Based on size of recipient and donor
- Harvest 10-15 mL/kg the patient's weight
- Maximum harvest volume is 15-20 mL/kg the donor
Harvest range Total Nucleated Cell count (TNC) - answer 1-4 x 10^8 mL/kg of recipient weight
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