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BMTCN CHAPTER 8 PROFESSIONAL PRACTICE WITH COMPLETE SOLUTIONS 2023
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BMTCN CHAPTER 8 PROFESSIONAL PRACTICE WITH COMPLETE SOLUTIONS 2023
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BMTCN CHAPTER 3 - PRETRANSPLANTISSUES WITH 100% CORRECT
ANSWERS
S.J. is about to undergo leukapheresis in preparation for an autologous transplant. The nurse
informs her that she may experience tingling in her lips and extremities during the procedure.
Which statement best explains this symptom?
A. Numbness and tingling are signs of a hypersensitivity reaction to the medications commonly
used for mobilization.
B. Paresthesia of the mouth and extremities may occur during leukapheresis because the
sodium citrate added to the blood to prevent clotting binds ion - answer B. Paresthesia of the
mouth and extremities may occur during leukapheresis because the sodium citrate added to the
blood to prevent clotting binds ionized calcium, causing serum hypocalcemia.
Plerixafor works to mobilize hematopoietic stem cells by which of the following mechanisms of
action?
A. The drop in white blood cells after receiving plerixafor leads to a transient, predictable
increase in circulating progenitor cells, which can be collected for hematopoietic stem cell
transplantation.
B. Plerixafor works by binding to certain cell surface receptors to stimulate the division and
differentiation of progenitor stem cells.
C. Plerixafor blocks the interaction between the chemokin - answer C. Plerixafor blocks the
interaction between the chemokine receptor CXCR4 and stromal-derived factor-1, causing stem
cells to be released from the bone marrow into the circulating blood.
P.J. is a 10-year-old female who requires an allogeneic transplant for leukemia. It is determined
that the patient's younger sister is a perfect human leukocyte antigen match. Plans are made to
begin the collection process as soon as possible. Which of the following is the best strategy for
the nurse to support the pediatric donor through the donation process?
A. Direct all teaching efforts to the parents to avoid causing the donor unnecessary stress.
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