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BMTCN REVIEW CHAPTER 8 - PROFESSIONAL PRACTICE QUESTIONS AND ANSWERS
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BMTCN REVIEW CHAPTER 8 - PROFESSIONAL PRACTICE QUESTIONS AND ANSWERS
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BMTCN CHAPTER 7: SURIVORSHIPISSUES WITH 100% CORRECT
ANSWERS
What is a patient who received a T-cell-depleted transplant at risk for developing within the first
year following transplant?
A. Acute myeloid leukemia
B. Breast cancer
C. Basal cell carcinoma
D. Post-transplant lymphoproliferative disorders - answer D. Post-transplant lymphoproliferative
disorders
What is the most common secondary malignancy in pediatric patients who receive radiation as
part of the transplant conditioning regimen?
A. Esophageal cancer
B. Thyroid cancer
C. Nonsquamous cell carcinoma
D. Brain stem glioma - answer C. Nonsquamous cell carcinoma
Which of the following is true of human papillomavirus (HPV) infections?
A. Exposure does not increase patients' risk of developing secondary cancers.
B. Because patients are not at a significant risk following transplant, vaccination is not
necessary.
C. HPV can significantly increase patients' risk of developing post-transplant lymphoproliferative
disorder.
, D. Patients between the ages of 9 and 26 should be revaccinated post-transplant with the HPV
vaccine. - answer D. Patients between the ages of 9 and 26 should be revaccinated post-
transplant with the HPV vaccine.
With which of the following are post-transplant lymphoproliferative disorders strongly
associated?
A. Donor B cells infected with the Epstein-Barr virus (EBV)
B. Donor T cells infected with EBV
C. They are not associated with viral infections.
D. Sibling myeloablative transplants - answer A. Donor B cells infected with the Epstein-Barr
virus (EBV)
Which of the following is NOT a risk for developing secondary solid tumors?
A. Genetic predisposition
B. Chronic graft-versus-host disease (GVHD)
C. An increased incidence within the first 12 months following transplant
D. Younger age at transplant - answer C. An increased incidence within the first 12 months
following transplant
Acute myeloid leukemia without features of myelodysplastic syndrome is most often associated
with patients who received which of the following?
A. Fractionated total body irradiation
B. Antithymocyte globulin (ATG)
C. A topoisomerase II inhibitor
D. An alkylating agent - answer C. A topoisomerase II inhibitor (doxorubicin, etoposide, and
mitoxantron)
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