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MIBO 3500 FINAL QUESTIONS WITH 100% CORRECT ANSWERS
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MIBO 3500 FINAL QUESTIONS WITH 100% CORRECT ANSWERS
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MIBO 3500 FINAL QUESTIONS WITH100% CORRECT ANSWERS
What bacterial species was associated with the discovery of penicillin by Alexander Fleming? -
answer Staphylococcus aureus
What are three different methods antimicrobials can work by? - answer peptidoglycan
differences in ribosome structure
biochemical pathway not found in humans
what type of applications can be used for drugs with low selective toxicity, such a
chloramphenicol? - answer neosporin, topical ointment, eye drops
for meningitis or extreme infections like bacteremia
Define selective toxicity - answer only kill one target
what do many bactericidal drugs inhibit? - answer cell wall synthesis
bactericidal or bacteriostatic?: elementary bot with bacteremia - answer bactericidal-- extreme
infection
bactericidal or bacteriostatic?: Woman on immunosuppressive drugs with a boil - answer
bactericidal-- immune system is compromised
bactericidal or bacteriostatic?: Middle aged body builder with strep throat - answer
bacteriostatic
bactericidal or bacteriostatic?: Pregnant woman with sinus infection - answer either-- pregant
, During growth in a closed batch system, during which phase of growth would vancomycin be
the most effective?
A) lag
b) log
c) stationary
d) death - answer Log phase
if gramicidin allows ions to pass freely through the cell membrane, how does it kill the bacterial
cell? - answer It creates a change in the osmotic pressure that can result in cytolysis of
plasmolysis
if DNA gyrase is inhibited by quinolones, how does DNA begin to unwind? - answer (normally:
unwinds DNA during replication to relieve torsional strain)
stress causes DNA to break, relieving supercoiling
What is translocation? - answer sliding of the ribosome down mRNA to the next codon
How could you counteract drug resistance involving enzyme that inactivates your drug? -
answer You need to know the STRUCTURE of the antibiotic
- chemically modify your drug
change the R group to make a new derivative (penicillin)
What could be a target for antiviral agents? - answer Viral assembly
attachment proteins
viral genome replication
What category of viruses would be affected by acyclovir? - answer ss DNA viruses and ds DNA
viruses
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