Temperature is regulated in the hypothalamus. The setpoint of the temperature can vary with a few
degrees.
There are several ways in which the body can regulate its temperature. Between a range (see graph
ppt) of atmosphere temperature, your body temperature is stable.
The setpoint of the body temperature changes also during exercise. The graph shows fever: fever
changes the setpoint: heating up the temperature.
During exercise you do produce heat, which rises your body temperature, but besides your setpoint
can increase.
During exercise there is metabolic activity. The heating of the body leads to an increase of body
temperature. This increase stops at some point, because evaporation and convection is possible:: this
is what the graph says. But this really depends on the setting. Besides the setpoint changes: this isn’t
included in the graph. In this way, the body can handle the high temperatures better. If the
temperature is higher, there are faster chemical reactions: benefitable! Because of the increase of
metabolic processes because of the increased temperature because of the increased temperature
setpoint, the body can handle exercise better.
Changes in all processes and temperatures are strongly dependent on conditions.
Dry heat is much better to tolerate than wet heat: in a vochtige environment you cant sweat.
Convection only takes place when your body temperature is lower than the environment
temperature.
Your skin temperature decreases due to the evaporation: due to the sweating, heath is extracted,
which leads to cooling of the skin: hopefully cool down the rest of the skin.
Sympathetic vasodilative cholinergic nerves: Acetylcholine is the neurotransmitter. They are the
neurotransmitter for cutaneous arterioles and sweat glands. The sweat glands are sympathically
stimulated, with the neurotransmitter acetylcholine.
When sweat glands want to sweat, they need fluid: you need blood flow to the sweat glands
vasodilatation needed. The vasodilative action of the vasodilative sympathetic system is needed for
the cold transfer.
Sympathetic vasoconstrictor nerve: Norepinephrine and neuropeptide are being secreted. This leads
to cutaneous vasoconstriction.
In the venous plexus the main part of the heat transfer takes place. Besides there go blood vessles to
the epidermis, which are cholinergic stimulated, and which go to the sweat gland.
The hypothalamic regulation of sweating
When your skin temperature, and when your dehydrated (so control of volume system!) you don’t
sweat so much: reduced sensitivity.
The more heat conductance through the skin, the more vasodilatation.
The warmer the skin is, the more you sweat.
When there is a lot of blood in the skin, all of this blood cant go to the muscle: so your exercise
capacity decreases. So it’s difficult to exercise very hard when it’s very warm, because a bigger part of
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