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Ventilatory mechanisms college
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Exercise physiology college
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Ventilatory mechanisms college blok 2.3Ventilation during exercise
When exercise begins the amount of ventilation increases about 4 fold. When exercise ends, it
doesn’t go back to the baseline, but remains elevated for a while.
The first increase of amount of ventilation is because of your brain. CO2 drops at the begin of
exercise: this doesn’t cause this increase of ventilation. When you start exercising, your motor
neurons that go to your muscles, also give some impulses to your respiratory centre. Besides
efferents of mechanoreceptors from joints and muscles might trigger respiratory centre.
The drop of CO2 is caused by the increase of ventilation.
There is a respiratory regulation centre in the medulla. Chemo receptors are very sensitive to CO2
later increasing the ventilation.
What limits VO2max?
In a healthy person, ventilation almost never limits the exercise.
When you reach your VO2 max, the pH drops: this means that your going towards anaerobic
metabolism. Your tissue doesn’t receive enough oxygen.
The arterial PO2 isnt the limiting factor: constant.
The Arterial PCO2 drops at the end, this means that ventilation is not the limiting factor.
You should train your cardiac function.
Lung function tests
These are important tests in early recognition of lunge disease.
The lung function is determined by 3 things, see ppt.
Peak flow meter: often used by people with asthma. There is a difference between men and women,
and it is depended of age as well. You can determine your airway resistence: for example before and
after using a medicine.
Spirometer: You can determine several volumes. You can not determine your residual volume. This
you can measure with helium dilution. You could breath from a container with a known amount and
concentration of helium. See ppt.
FEV1 measurement: You measure the airway resistance. You can distinguish between restrictive and
obstructive disease.
80% of your vital capacity you normally can exhale in 1 second.
Obstructive disease: Your FEV and FVC both decreases, but the amount of FEV of FVC (tiffeneau index)
decreases.
Restrictive disease: Both FEV and FVC decrease, but the tiffeneau index remains the same or
increases.
Pneumo-tachograph: ppt.
With this technique you can also make a flow-volume plot, to measure the lung function.Here you
see that your flow decreases as your lungs become smaller.
Obstructive disease: some of your airways will collapse, and increase further yourresistence. Your
residual volume increases: the curve shifts to the left.
Restrictive disease: curve shifted to the right: residual volume decreases.
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