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Exam (elaborations)

CPHON EXAM Flashcards LATEST UPDATE

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CPHON EXAM Flashcards LATEST UPDATE...

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  • November 21, 2023
  • 23
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
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CPHON EXAM Flashcards LATEST UPDATE



What medications can relieve dyspnea in terminal patients? - ANSWER Opioid drugs (oral
and inhaled)

Scopalamine reduces secretions.

What is the purpose of a phase IV trial? - ANSWER To further investigate the long term
safety and efficacy of a treatment.

*Goal is to decrease long term side effects while providing acceptable cure rates.

What does the Candlelighters organization do? - ANSWER Provide cancer survivors with
information and counsel on their legal rights.

What did the National Cancer Act of 1972 do? - ANSWER Started the "war on cancer".

Gave the NIH more funding/strength for cancer research.

Which drugs are classified as hormones? - ANSWER dexamethasone

prednisone

hydrocortisone

Is fever an emergency for people with sickle cell disease? - ANSWER Yes, ALWAYS.

Sickling will occur at a higher rate with fever.

What would indicate a good vs poor prognosis in leukemia? - ANSWER Good =
hyperdiploidy

Poor = positive for Philadelphia Chromosome (9;22)(q34; q11) translocation.

What age group has the best prognosis in neuroblastoma? - ANSWER Less than 12 months
old.

Where is osteosarcoma most commonly found initially? - ANSWER The long bones:

tibia, femur, humerus

Why is rotationplasty pereferred surgically for osteosarcoma patients? - ANSWER Better
functionality.

What are the causes and symptoms of posterior fossa syndrome? - ANSWER Transient

,defecits after PF surgery. Present 24-48 hours after surgery and last 2 - 6 months.

Speech disturbance, dysphagia, decreased motor function, emotional lability, cranial nerve
palsy.

What is the treatment for posterior fossa syndrome? - ANSWER OT/PT/Speech

correct hydrocephalus

sometimes glucocorticoids

What is a classic clinical presentation of retinoblastoma? - ANSWER Leukocoria "cat's eye
reflex"

Caused by pressure on the retina.

What are the major toxicites of hormones? - ANSWER altered metabolic function

decreased bone density

(/C)

Which drugs are classified as miscellaneous non-cell cycle specific agents? - ANSWER
asparaginase

retinoids (atra, accutane)

(/C)

What type of pain do terminal children experience? - ANSWER disease related (rapid
onset)

bone/nerve (longer duration)

Name some symtoms seen with brain tumors. - ANSWER facial/cranial nerve palsy

speech and swallowing difficulty

ataxia

seizures

emotional/personality changes

What type of cancer is characterized by blue Reed-Sternberg cells? - ANSWER Hodgkin's
Disease

*cells look like owl eyes

, What does the presence of Auer Rods in microscopic bone marrow reivew indicate? -
ANSWER That the patient has non-lymphacitic leukemia.

It's not ALL, usually AML or CML.

Looks like black rods in cells.

What do neutrophils do? - ANSWER Act as the first line of defense against antigens.

Nonspecific.

What would be considered severe aplastic anemia? - ANSWER ANC <500

Platelets <20K

What long-term side effect can carmustine (BCNU) cause? - ANSWER Pulmonary
dysfunction.

How do you calculate absolute neutrophil count (ANC)? - ANSWER (%bands+%segs)Xtotal
WBC = ANC

What would you expect to see in a newly diagnosed Burkitt's Lymphoma patient? - ANSWER
Rapidly enlarging abdominal mass

Elevated LDH

What are some characteristics of Langerhans Cell Histiocytosis (LCH)? - ANSWER
presentation with scaly red papules

causes breakdown in bony areas

What are some characteristics of immune thrombocytopenic purpura (ITP)? - ANSWER
Low platelets

presents with bruising, purpura, pettichiae, but RARELY BLEEDING

What are some presenting symptoms of Wilms Tumor? - ANSWER Hematuria

Hemihypertrophy

What lab values are associated with tumor lysis syndrome? - ANSWER Think: Pup goes up!

Potassium >6, Uric Acid >8, Phosphorus >10

Calcium <8

What are the symptoms of syndrome of inappropriate antidiuretic hormone secretion

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