Summary
Histologie samenvatting Klierweefsel
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Dit is een samenvatting van het hoofdstuk 'Klierweefsel' van het vak histologie. Dit vak wordt gedoceerd in de 1e bachelor van de opleiding Biomedische wetenschappen.
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HT 5: klierweefselKlierepitheel
Kliercellen = cellen die gespecialiseerd zijn in afgave van substanties aan inwendig of uitwendig
milieu (=secretie)
Substanties = secretieproduct of secreet
Niet alle secreterende cellen zijn kliercellen
Vb. bindweefselcellen, zenuwcellen (secreteren neurotransmitters), immuniteitssysteem
Eencellige klieren liggen verspreid tss dekepitheelcellen (bv. slijmbekercel)
Meercellige klieren (klierweefsel):
o Georganiseerd tot klier
o Deel van ander orgaan
Secretiecyclus
3 processen:
1) Ingestiefase: opnemen van bouwstenen (basale zijde)
Restauratiefase (overlappen)
2) Accumulatiefase: synthese & opstapeling van secreet
(in celorganellen)
3) Rustfase
4) Extrusiefase: afgave v secreet (in vesikels
aan apicale zijde; exocytose)
Monofasisch vs polyfasisch
1 keer of cyclus meerdere keren
Afgifte continu of door prikkel
, Ontstaan
Specialisatie uit epitheel
Knopje -> uitstulping: in verbinding (exocriene klier) of verlies verbinding (endocriene klier =
afgaven aan bloed)
Exocriene klieren
Unicellaire klieren tss dekepitheel
Vb. slijmbekercellen
Klierweefsel
o Groepen afgewisseld met dekepitheel: klierblad of -plaat
o Onder dekepitheel
Polariteit:
o Basaal: kern en meeste celorganellen, golgi-apparaat supranucleair
o Apicaal: secretiegranula
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