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CPPS 304 New /56 Questions And Answers
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CPPS 304 New 2023-2024 /56 Questions And AnswersQuiz :Receptor - Answer :Macromolecule whose biological function changes
when a drug binds to it
Quiz :What are the link between chemical actions and biological function? -
Answer :Receptors
Quiz :Emax - Answer :maximum effect of a drug
Quiz :What happens when Emax is reached? - Answer :Emax occurs when all
receptors are bound
Quiz :What is in indication that spare receptors are present? - Answer :When
Emax is reached before all receptors are bound
Quiz :Agonist - Answer :has affinity for a receptor as well as intrinsic activity at
the receptor
Quiz :Antagonist - Answer :has affinity for a receptor but no intrinsic activity
at the receptor
Quiz :partial agonist - Answer :has affinity for a receptor but lacks the full
intrinsic activity of an agonist
Quiz :inverse agonist - Answer :binds to a constitutively active receptor and
inactivates it
Quiz :affinity - Answer :the propensity of a ligand to bind to a receptor
Quiz :high affinity = - Answer :binds readily to a receptor
Quiz :low affinity = - Answer :spends less time bound to a given receptor
Quiz :intrinsic activity - Answer :the action carried out by the ligand while it is
bound to a receptor
Quiz :Kd - Answer :dissociation constant (affinity of a drug for a receptor)
Quiz :What does the value of Kd signify? - Answer :measures the propensity
of a drug to release (dissociate) from a receptor
, Quiz :What does a high Kd mean? - Answer :drug readily dissociates from its
receptor
Quiz :What does a low Kd mean? - Answer :suggests high affinity for its
receptor
Quiz :If a patient were to overdose on a reversible antagonist, what could you
do? - Answer :Add more agonist
Quiz :Irreversible or Non-Competitive Antagonists - Answer :bind to receptor
for life
Quiz :Reversible or Competitive Antagonists - Answer :bind and release from a
receptor and are in a constant state of flux
Quiz :True or False, increasing the concentration of agonist will overcome the
effects of an irreversible antagonist. - Answer :False
Quiz :What are the four types of receptors? - Answer :Ion channel, G-protein
coupled, Coupled to enzymes, Intracellular
Quiz :What type of receptor involves Acetylcholine? - Answer :Ion channel
Quiz :What is the fastest type of receptor? - Answer :Ion channel
Quiz :What type of receptor involves adrenergics like epinephrine? -
Answer :G-protein coupled
Quiz :What is the most common receptor type? - Answer :G-protein coupled
receptor
Quiz :What type of receptor involves receptors dimerizing after being bound
by a ligand? - Answer :Coupled to Enzyme Receptors
Quiz :Growth factors and insulin are involved in which type of receptor? -
Answer :Coupled to Enzyme Receptors
Quiz :What is the slowest type of receptor? - Answer :Intracellular
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