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Samenvatting celbiologie - hoofdstuk cytoskelet $4.34   Add to cart

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Samenvatting celbiologie - hoofdstuk cytoskelet

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  • Course
  • Institution

prof Geert callewaert

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  • March 1, 2018
  • 13
  • 2017/2018
  • Summary

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By: ademan • 6 year ago

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6. CYTOSKELET




KLEINST

GROOTST




 Keyfuncties vh cytoskelet
1. structuur & support
2. Intracellulair transport
3. Contractiliteit en motilitiet

TRANSPORT



Amoeboëde
voortbewegin
g




DELINGSSPOEL

SPIERCONTRACTIE

, 1. Structuur en organisatie van actine filamenten
 Voedselinfecties en actine filamenten
 Listeria monocytogeneses – listeriosis
= bacterie

-OORZAAK & SYMPTOMEN

 Bacterie die voorkomt is besmet voedsel (rauwe melk, rauw vlees,…)
 Komt in darmkanaal & dringt slijmvlies binnen
o Zorgt voor griepachtige symptonen
 Koorst
 Rillingen
 Hoofdpijn
 Kan zorgen voor hersenvliesontsteking, ooginfecties, sepsis (bloedvergifting)

-WAT?

 Maakt misbruik van actinefilamenten om zich te transporteren id cel en zo andere
cellen te infecteren.

-LYSTERIA LIFECYCLE

 Beweegt dankzij actine filamenten (komeetstaart – paars)
 Duwt de bacterie voort
 Bacterien duwen tegen celwand  vormen pseudopodie
(uitstulping celw)
 Kunnen zo via fagocytose in andere cel binnenkomen
 VOORDEEL: bacterie komt nooit buiten de cel




 Actine & actine-bindende proteïnen (ABP’s)
 Overzicht
- Actinefilamenten: 1. G-actine (globulair – 1 actinemolecule)
2. F-actine (2 ketens gepolymeriseerde G-actinen die helix vormen -
filamentlus – dubbelstreng –)

 heel wat eiwitten interageren hiermee

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