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Oral Pathology Clinical Pathologic Correlations 7th Edition by Regezi - Test Bank
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,Chapter 1: Vesiculobullous DiseasesTest Bank
MULTIPLE CHOICE
1. Intercellular deposits of IgG are consistently found in oral epithelium in which of the
following?
a. Cicatricial pemphigoid
b. Lichen planus
c. Pemphigus vulgaris
d. Stevens-Johnson syndrome
e. Aphthous ulcers
ANS: C REF: Chap 1 (Pemphigus vulgaris/Etiology and pathogenesis), p 11
2. A patient seeks help for recurrent palatal pain. She presents with multiple punctate ulcers in
the hard palate that were preceded by tiny blisters. Her lesions typically heal in about 2 weeks
and reappear during stressful times. She has:
a. Aphthous ulcers
b. Recurrent primary herpes
c. Recurrent secondary herpes
d. Erythema multiforme
e. Discoid lupus
ANS: C REF: Chap 1 (Herpes simplex infection/Pathogenesis), pp 1-3
3. All but one of the following are contagious and thus are potential occupational hazards to the
dentist and dental hygienist. Choose the noncontagious condition.
a. Oral histoplasmosis
b. Pemphigus vulgaris
c. Cold sores
d. Primary herpes
e. Oral chancre
ANS: B REF: Chap 1 (Pemphigus vulgaris), pp 11-15
4. A 55-year-old man presents with a single deep indurated crateriform lesion of the posterior
lateral border of the tongue. It is asymptomatic. This could be all of the following except:
a. Squamous cell carcinoma
b. Chronic traumatic ulcer
c. Secondary herpes
d. Syphilis
e. Histoplasmosis
ANS: C REF: Chap 1 (Herpes simplex infection/Box 1-2), p 4
5. Bilateral buccal mucosal white lesions would be expected in all the following except:
a. Cannon’s disease (white sponge nevus)
b. Witkop’s disease (HBID)
c. Secondary herpes zoster
Copyright © 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.
, Test bank 2
d. Leukoedema
e. Cheek chewing
ANS: C REF: Chap 1 (Varicella-zoster infection), pp 6-8
6. Which of the following vesiculobullous disorders is nonhereditary and occurs almost
exclusively on the skin?
a. Pemphigus vulgaris
b. Cicatricial pemphigoid
c. Epidermolysis bullosa
d. Lupus erythematosus
e. Bullous pemphigoid
ANS: E REF: Chap 1 (Bullous pemphigoid), pp 17-18
7. Which of the following conditions exhibits subepithelial separation microscopically?
a. Pemphigus vulgaris
b. Mucous membrane pemphigoid
c. Aphthous stomatitis
d. Secondary herpes simplex
e. None of the above
ANS: B
REF: Chap 1 (Mucous membrane pemphigoid/Histopathology and immunopathology), pp
16-17
8. The palate and maxillary ridge of a 56-year-old woman contain multiple flat ulcers of 8
weeks’ duration. She has a positive Nikolsky sign and has no evidence of skin or lip lesions.
Which of the following should receive serious consideration in the clinical differential
diagnosis?
a. Pemphigus vulgaris
b. Herpangina
c. Lichen planus
d. Aphthous stomatitis
e. Herpes simplex infection
ANS: A REF: Chap 1 (Pemphigus vulgaris), pp 11-15
9. A 22-year-old woman complains of mildly painful ulcers in her hard palate. The ulcers are
multiple and confluent. A similar condition has been noted in the patient on two previous
occasions. This is most likely:
a. Trauma
b. Herpangina
c. Candidiasis
d. Riga-Fede disease
e. Secondary herpes
ANS: E
REF: Chap 1 (Secondary, or recurrent, herpes simplex infection), pp 3-4
Copyright © 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.
, Test bank 3
10. Cytologic examination can be diagnostic of which of the following diseases?
a. Herpes simplex
b. Recurrent aphthae
c. Mucous membrane pemphigoid
d. Erosive lichen planus
e. Frictional hyperkeratosis
ANS: A REF: Chap 1 (Herpes simplex infection/Histopathology), p 5
11. The Tzanck cells in pemphigus vulgaris result from:
a. Acantholysis
b. Acanthosis
c. Intercellular edema
d. Intracellular edema
e. Mucous extravasation
ANS: A
REF: Chap 1 (Pemphigus vulgaris/Histopathology and immunopathology), pp 11-14
12. Site specificity is a characteristic clinical feature of which of the following conditions when it
occurs intraorally?
a. Syphilis
b. Candidiasis
c. Histoplasmosis
d. Intraoral tuberculosis
e. Secondary herpes simplex infection
ANS: E
REF: Chap 1 (Secondary, or recurrent, herpes simplex infection), pp 3-4
13. Herpes simplex infections are most rationally treated with:
a. Lysine
b. Topical clobetasol
c. Acyclovir
d. Topically applied tetracycline
e. Prednisone
ANS: C REF: Chap 1 (Herpes simplex infection/Treatment), p 6
14. A middle-aged man developed multiple flat ulcers in his palate, tongue, and buccal mucosa.
The lesions measured approximately 1 cm in diameter and were preceded briefly by bullae.
The lesions have been persistent for 6 weeks. He has no skin, eye, or genital lesions. Biopsy
shows acantholysis with intraepithelial separation. He most likely has:
a. Erythema multiforme
b. Discoid lupus erythematosus
c. Primary herpes simplex infection
d. Mucous membrane pemphigoid
e. None of the above
ANS: E
Copyright © 2012, 2008, 2003, 1999, 1993, 1989 by Saunders, an imprint of Elsevier Inc.
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