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Pharmacology for Rehabilitation Professionals 2nd Edition by Gladson - Test Bank
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,Gladson: Pharmacology for Rehabilitation Professionals, 2nd EditionChapter 01: Introduction
Test Bank
MULTIPLE CHOICE
1) The effectiveness of a drug in large populations is the subject of __________.
A. pharmacogenomics
B. pharmacodynamics
C. pharmacoepidemiology
D. pharmacokinetics
ANS: C
Pharmacogenomics studies the genetic basis of drug responses. Pharmacodynamics studies
drug- receptor interactions. Pharmacokinetics studies the fate of a drug in the body.
2) Rehabilitative therapists should know pharmacology because __________.
A. drugs can cause effects which interfere with physical therapy
B. proper drug administration scheduling can help physical therapy
C. certain therapies like hot baths can seriously interact with certain drugs
D. All of the above
ANS: D
3) Approval for marketing of a drug is done by the __________.
A. Food and Drug Administration
B. U.S. Health Department
C. American Medical Association
D. National Institute of Health
ANS: A
The U.S. Health Department, American Medical Association, and National Institute of
Health might advise but do not approve.
4) Before a drug is approved, the company must submit data verifying that the drug
__________.
A. is efficacious
B. has acceptable toxicity
C. should be marketed at a particular dose and indication
D. All of the above
Copyright © 2011, 2006 by Saunders, an imprint of Elsevier Inc.
,Test Bank 1-2
ANS: D
5) Clinical trials of a new drug are divided into 4 phases. Which description is correct?
A. Phase I tests the drug in only 20 patients who are mildly ill.
B. Phase II tests the drug in about 40-50 patients who are seriously ill.
C. Phase III tests the drug in about 3000-10,000 patients.
D. Phase IV re-tests the drug in about 500 patients who were previously drug non-
responders.
ANS: C
Phase I uses healthy volunteers. Phase II tests about 100-200 patients. Phase IV begins when
the drug is approved for public use. No phase deals with drug non-responders.
6) To bring a new drug on the market takes about __________.
A. 1 year
B. 5 years
C. 8 years
D. 12 years
ANS: D
It takes about 12 years including 3-4 years for preclinical studies and about 8-9 years for
Phase I-III studies at a cost of about $800 to 100 million.
7) A prescription must contain all of the following information except __________.
A. physician’s name, credentials, address, telephone number, and signature
B. the drug name, dose and how the drug is to be administered
C. the patient’s full name and address
D. the name of the pharmacy that is supposed to fill the prescription
ANS: D
The pharmacy can be selected by the patient but all the other information must be provided.
8) Controlled substances are divided into schedules. Which of the following schedule
descriptions is false?
A. Schedule I: Substances used for research only with no clinical use.
B. Schedule II: Drugs with a high potential for physical and psychological abuse but limited
medical use with no refills.
C. Schedule III: Drugs with moderate potential for abuse and wider therapeutic use but refills
allowed.
D. Schedule IV: Drugs with no potential for abuse and wide therapeutic use and unlimited
refills allowed.
Copyright © 2011, 2006 by Saunders, an imprint of Elsevier Inc.
, Test Bank 1-3
ANS: D
Drugs with mild to moderate potential for abuse are included in schedule IV.
9) Morphine, fentanyl and oxycodone are in schedule __________.
A. I
B. II
C. III
D. IV
ANS: B
Only opioids, which are formulated with aspirin or acetaminophen, fall in schedule III.
10) The year it was required that marketed drugs be shown by the pharmaceutical company
to be both efficacious and relatively safe is __________.
A. 1855
B. 1909
C. 1934
D. 1962
ANS: D
The Kefauver-Harris Amendments to the Food, Drug, and Cosmetic Act required evidence of
both efficacy and relative safety and were signed in 1962.
11) The abbreviation prn stands for __________.
A. as needed
B. every day
C. before meals
D. twice a day
ANS: A
Every day is ad, before meals is ac, and twice a day is bid.
12) The official medical name of a drug is the __________.
A. chemical name
B. brand name
C. proprietary name
D. generic name
ANS: D
All the other names are secondary names important for research and/or marketing.
Copyright © 2011, 2006 by Saunders, an imprint of Elsevier Inc.
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