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Summary phys.theory: MS introduction

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Summary of the MS intro lesson given by prof G.Verheyden from the course of physiotherapeutic theory. It is a summary of the powerpoint slides and additional items noted during the lesson. The slides were in English and my own notes are always in Dutch as much as possible. It is therefore a mix of ...

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  • December 17, 2023
  • 22
  • 2023/2024
  • Summary
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Phys theory: MS: intro
Disease course & global evaluation

 Chronic progressive disease with inflammation and degeneration processes in the brain and spinal cord
 Leasie in hersenen
 Leaie in RM= meer impact dan in motor area’s
- Veel tracts multiple tracts
- MS=white matter aangevallen (myeline)
- RM= weinig / geen mogelijkheid neuroplast.
- MS= kan nog neuroplast. Zijn
 Hypertonia/spast in MS ≠ hersenen of RM leasie
- RM meer gelokaliseerd in een reflexogene manier
- Type/pheothype
- In RM= meer prob onder leasie
- Meer risico spasme abductie &flex&extensie
 Diagose moet snel gesteld worden
 Kripen hersenen= mindr plek voor uitvoeren complexere taken
- Geen neuroreserve meer
 Diagnose kan makkelijker & technischer gemaakt worden
- Vroeger = min 2 symptome vertonen
 Vaak pas zeer laat diagnose krijgen
- Vroeger minder gefocusd op sec. progressie
 Meer op relapsing-remitting
- CIS clinically important symptoms (figuur)

 Differentiation between inflammation and degeneration
- Manifistations in P are different
- Lot of inflammation -> medication
- If not it is a questionmark…
- With matter lesions on the T2 scan, it can also occur in the SC

1. DIFFERENT TYPES OF MS
 ‘Relapsing-remitting’ versus
‘progressive MS’
 ‘Active’ versus ‘non-active’
 The classification that we know now,
but this will change, there are
researches happening
 CIS can be active or not active
 When the symptom doesn’t come back
it is not active
 Active can lead to a RRMS when it does
come back several times
 RRMS
- Active: a lot of lesions in the brain
that progress
- Not-active: not that much lesions in the brain, and no progression in the brain

 Active & met progressive
- Active= Elke 2 j. scan & verergering zien
- Progressive= symptome




Nala Melis Pagina 1

, Phys theory: MS: intro




1.1. PROGRESSIVE MS




1.2. RRMS – PIRA
 Progression In absence of Relapse Activity
 PIRA: there can be a progression happening but very
subtle
 Typically in RRMS
 We should measure the activity and the progression to
know how the patient is doing
 Behavioural changes that may be happening
 T25-FW=time 25 foot walk
- 7.62m zo snel mogelijk
- Wandelsnelheid
 Misschein eerder kijken naar activiteit ipv progressie




Nala Melis Pagina 2

, Phys theory: MS: intro

2. CLINICAL COURSE OF MS
 Future: new names and terms
 Maybe the 2 questionmarks will emerge
 There is always a progression?




 Neurodegenerative disease: it is present in the early phase but not realy visible, think about PIRA!
 Health behaviour: smoking is proven to be very negative for your progression
 Not every patient benefits from drugs (medication)

3. Disease Modifying drugs (DMD) for RRMS / PMS




4. SYMPTOMS
 Veel invissible symptomen
- Cogitieve functie,…
 Fatigue= numer 1
 Ahankelijk per P welke symptomen
 Pijn
- Neuorplastisch
- Neuropatisch
 Emotional changes

 Symptomen
- Fatigue
- Weakenss
- Spasms
- Cognition
- Depression
- Reduced walking
- Sensory-loss
- Balance problems
- Increased temperature will lead to a worse performance
- Dual tasking problems
 Symptom interconnectivities

Nala Melis Pagina 3

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