What medications can relieve dyspnea in terminal patients? ✔️Ans - Opioid
drugs (oral and inhaled)
Scopalamine reduces secretions.
What is the purpose of a phase IV trial? ✔️Ans - To further investigate the
long term safety and efficacy of a treatment.
*Goal is to decrease long term side effects while providing acceptable cure
rates.
What does the Candlelighters organization do? ✔️Ans - Provide cancer
survivors with information and counsel on their legal rights.
What did the National Cancer Act of 1972 do? ✔️Ans - Started the "war on
cancer".
Gave the NIH more funding/strength for cancer research.
Which drugs are classified as hormones? ✔️Ans - dexamethasone
prednisone
hydrocortisone
,Is fever an emergency for people with sickle cell disease? ✔️Ans - Yes,
ALWAYS.
Sickling will occur at a higher rate with fever.
What would indicate a good vs poor prognosis in leukemia? ✔️Ans - Good =
hyperdiploidy
Poor = positive for Philadelphia Chromosome (9;22)(q34; q11) translocation.
What age group has the best prognosis in neuroblastoma? ✔️Ans - Less
than 12 months old.
Where is osteosarcoma most commonly found initially? ✔️Ans - The long
bones:
tibia, femur, humerus
Why is rotationplasty pereferred surgically for osteosarcoma patients?
✔️Ans - Better functionality.
What are the causes and symptoms of posterior fossa syndrome? ✔️Ans -
Transient defecits after PF surgery. Present 24-48 hours after surgery and last
2 - 6 months.
, What is the treatment for posterior fossa syndrome? ✔️Ans -
OT/PT/Speech
correct hydrocephalus
sometimes glucocorticoids
What is a classic clinical presentation of retinoblastoma? ✔️Ans -
Leukocoria "cat's eye reflex"
Caused by pressure on the retina.
What are the major toxicites of hormones? ✔️Ans - altered metabolic
function
decreased bone density
(/C)
Which drugs are classified as miscellaneous non-cell cycle specific agents?
✔️Ans - asparaginase
retinoids (atra, accutane)
(/C)
What type of pain do terminal children experience? ✔️Ans - disease related
(rapid onset)
bone/nerve (longer duration)
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