BSNC 1000 – PERFUSION LATEST 2023 GRADED A+

BSNC 1000 – PERFUSION LATEST 2023 GRADED A+ Radius Biggest affect on blood flow through a vessel Activation of Sympathetic NS - Decreases vessel diameter - Increases CO - Increases TPR Perfusion The supply of oxygen to and removal of wastes from the cells and tissues of the body as a result of the flow of blood through the capillaries. Arterial System Distributes blood and regulates pressure Capillary beds Transfer of materials between circulation and tissues Venous System Returns blood to heart volume reservoir Scope of Perfusion Optimal - Impaired - No Perfusion Ischemia (cell injury) Impaired perfusion Infarction (cell death) No Perfusion Blood Pressure Force of blood against the walls of blood vessels Systolic Pressure BP during systole - ventricles contract Diastolic Pressure BP during diastole - ventricles relax Pulse Pressure Systole - Diastole (normal = 40-45 mmHg) MAP = CO x TPR MAP ≈ Diastolic Pressure - 1/3(Partial Pressure) Blood Volume Influenced By: -sodium ingestion and excretion -renin/aldosterone Vasoconstriction Influenced By: - Autonomic NS - Kidney renin/angiotensin - Adrenal medulla hormones Cardiac Output Influenced By: - BPM - Volume of blood Peripheral Resistance Influenced By: - Vasoconstriction - Vasodilation - Local Factors (pH, hypoxia) - Sympathetic stimulation of smooth muscle of vessel walls - Blood viscosity - Vessel radius Vasodilation Influenced By: - Autonomic NS - Kidney: vasodilators - Hormonal factors Peripheral Resistance Force that must be overcome to push blood through the circulatory system Blood Viscosity Decreases Because: - Anemia