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Samenvatting EBD3: farmacologie en biochemie $6.09   Add to cart

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Samenvatting EBD3: farmacologie en biochemie

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Een samenvatting van de twee gastlessen over farmacologie, labowaarden, fytotherapeutica en voedingssupplementen. Telt 12 pagina's.

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  • January 2, 2024
  • 13
  • 2023/2024
  • Summary
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FARMACOLOGIE-BIOCHEMIE
INHOUDSOPGAVE

labowaarden ...............................................................................................................................................................................2

nierfunctie ........................................................................................................................................................................................2
welke laboparameters .................................................................................................................................................................2
not to forget .................................................................................................................................................................................3

leverfunctie .......................................................................................................................................................................................3
welke laboparameters .................................................................................................................................................................3

infectieparameters ...........................................................................................................................................................................4
leukocytose (verhoging witte bloedcellen) ..................................................................................................................................5
Crp (c-reactief proteïne) ...............................................................................................................................................................5
bloedbezinkingssnelheid ..............................................................................................................................................................5

natrium en kalium ............................................................................................................................................................................5
hyponatriëmie ..............................................................................................................................................................................6
hypernatriëmie.............................................................................................................................................................................6
hypokaliëmie ................................................................................................................................................................................6
hyperkaliëmie ...............................................................................................................................................................................7
natrium en kalium in een notendoop ..........................................................................................................................................7

glycemie ...........................................................................................................................................................................................7
geglycosyleerde of versuikerde hemoglobine .............................................................................................................................7
orale glucose tolerantie test ........................................................................................................................................................8

tot slot ..............................................................................................................................................................................................8

fytotherapie en voedingssupplementen ......................................................................................................................................8

voedingssupplementen vs. fytotherapeuticum ................................................................................................................................8
farmacognosie ..............................................................................................................................................................................9
voedingssupplement of fytotherapeuticum ................................................................................................................................9
ambivalente planten ....................................................................................................................................................................9

toepassingen met betrekking tot kankertherapieën ........................................................................................................................9
preventief .....................................................................................................................................................................................9
behandelend ..............................................................................................................................................................................10
ondersteunend/symptomatisch .................................................................................................................................................10

problematiek van interacties..........................................................................................................................................................11
voorbeelden van potentiële interacties .....................................................................................................................................11

wat met cannabis? .........................................................................................................................................................................12
welke medisch gebruikte preparaten en producten van cannabis bestaan er? ........................................................................12
is er enig wetenschappelijke onderbouwing dat medisch gebruikte cannabis werkt?..............................................................13
zijn er interacties? ......................................................................................................................................................................13
roken vs. orale inname ...............................................................................................................................................................13




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, LABOWAARDEN

NIERFUNCTIE

− Groot aantal microscopisch kleine filtertjes die bloed zuiveren
− Eliminatie afvalstoffen, geneesmiddelen, metabolieten (klaring geneesmiddelen → metabolieten uitscheiden in urine)
− Nierfunctie verhoogd: hyperklaarders; meer en sneller
− Nierfunctie verlaagd: nierinsufficiëntie


WELKE LABOPARAMETERS
− Bloedstaal
o Concentratie serumcreatinine → geschatte glomerulaire filtratiesnelheid (eGFR)
▪ Hoeveel bloed kunnen de nieren filteren/zuiveren per minuut
▪ Uitgedrukt in ml/min/1,73m2
− Urinestaal
o Concentratie eiwitten (albumine): albuminurie (niet de bedoeling dat er eiwitten in urine zitten)




SERUMCREATININE
− Afbraakproduct van de spieren
o Mensen met veel spieren: meer creatinine
o Ouderen: minder spieren dus minder creatinine
− Wordt bijna volledig glomerulair gefiltreerd: dus goede laboparameter om de nierfunctie in te schatten
− Verschillende wiskundige formules om op basis van het serumcreatinine de GFR in te schatten
o Cockroft en Gault
o MDRM
o CKD-EPI




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