Summary
Samenvatting Overzicht pathologie van de mond
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Overzichtstabel verschillende aandoeningen mond Klinische benadering van beelden Aangevuld met lesnota's Enkel deel Dr. Coopman
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PATHOLOGIE VAN DE MOND (Dr. Coopman)Belangrijkste concepten examen
● Indien bilaterale lesies
o Minder kans op maligniteit
o Denken aan systemische aandoening (vb. Ziekte van Crohn)
● Wanneer geen aften → maligniteit
o Niet recidiverend
o Solitair
o Zelfde lokalisatie
o > 3 weken
o Ongewone lokalisatie: mondbodem, laterale zijde tong
o Eerste keer op oudere lftd
o Eerst vesikel
o Eerst leukoplakie of erythroplakie
NIET NEOPLASTISCHE LESIES VAN DE MONDMUCOSA
Opdeling
● Ulceratie: schade aan epitheellaag
o Oppervlakkig defect door weefselverval
o Geringe neiging tot genezing
o Huid of mucosa
o Opdeling
▪ Primair: aften, trauma, behçet
▪ Secundair: huid-slijmvlies aandoeningen, infectie (viraal, bact), medicatie
● Witte afwijking
o Afschraapbare
▪ Candida
o Niet afschraapbare
▪ Lokale factoren
▪ Wang: linea alba, leukoedeem, white sponge nevus
▪ Tong: stomatitis nicotina, lingua geografica, lingua villosa
▪ Leukoplakie !!
▪ Lichen planus, lichen sclerosus
,● Rode afwijking
o Tongafwijkingen
▪ Glossitis rhomboidea mediana
▪ Tong Zwelling
● Amyloidose
● Macroglossie
● Syndroom van cowden
● Ductus thyreoglossus cyste
● Tongstruma
● Granulaircel tumor
o Lipafwijkingen
▪ Cheilitis angularis
▪ Cheilitis exfoliativa
▪ Cheilitis fissurata
▪ Cheilitis glandularis
▪ Cheilitis granulomatosa
▪ Mucocele
▪ Pyogeen granuloom
▪ Epulis
▪ Gingiva hyperplasie
o Vasculaire afwijkingen
▪ Angina haemorrhagica bullosa
▪ Flebectasie
▪ Hemangioom
▪ Arterioveneuze malformatie
▪ Kaposi sarcoom
o Papilloma
o Fibroom
o Lipoom
o Lymfangioom
, PREMALIGNE LESIES VAN DE MONDMUCOSA
● DD benigne - dysplasie - maligne
○ Benigne: mooie afkapseling en mooie vorm
■ R/ verwijderen kapsel = verwijderen tumor
○ Dysplasie: gn normale structuur, meerdere mitotische kernen maar basaal membraan intact
○ Premaligne: een morfologisch veranderd weefsel m hoger risico op ontaarding tov gezond weefsel
○ Maligne: doorheen basale membraan, infiltratief naar stroma, anaplasie (afwezigheid normale celstructuur)
● Opdeling
● Leukoplakie
● Erythroplakie
● Actinische cheilitis
● Keratoacanthoom
● Pigmentaties
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