Summary
Samenvatting spierweefsel
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dit is uit het boek , slides, notities van patric calders
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H5Spierweefsel
Dwarsgestreepte spierweefsel :
1) Skeletspierweefsel
2) Hartspierweefsel
Glad spierweefsel
Gemeenschappelijke kenmerken :
- Mogelijkheid tot conductie en contractie
1. Dwarsgestreepte skeletspierweefsel
1) Het skeletspierweefsel
- Ontstaan : 1kernige myoblasten versmelten tot syncytia = meerdere
kernen
- Kern : perifeer
Contractiele elementen : specifieke ordening
- Mature skeletspiercel = kan lang worden = SPIERVEZEL
- Macroscopisch
- Rond spier : dunne bindweefselhuls =
ENDOMYSIUM
- Groep vezels = BUNDEL
- Bundels omgeven door dikkere
bindweefsellaag = PERIMYSIUM
- Aantal spierbundels omgeven door
stevige bindweefsel huls = EPIMYSIUM
- Einde spier = PEES
- Pees eindit op periost v/h bot = ( spier
vast zit )
- Omgeven door fascia
Spiervezel = aparte innervatie
, - Lichtmicroscopisch
- Longitudinale doorsnede = parallel geschikt lange ,veel kernige cellen
- KERN : perifeer geschikt , onder SARCOLEMMA ( celmembraan spiervezel)
- Sacroplasma = fijne lengtestreping v myofibrillen en dikkere dwarsstreping
met periodische afwisselende licht ( I of isotrope) en donkere ( A of
anistrope) banden
- I/ isotrope = fijne lijn = Z-lijn ( zwischenscheibe)
= dwarsstreping van
skeletspiervezels
- Elektronenmicroscopisch
Contractiele eiwitten :
- = myofibrillen = * contractiele proteïnen
* actine =cilindrisch en parallel
* myosine
- Myosinefilamenten (15 nm ) = hoogdbestanddeel van de A-band
( actinefilamenten ( 5nm) bouwen de I-band op
- Midden I-band = actinefilamenten overvlechten elkaar = Z -schijf
- Afstand tss 2 Z-schijven = SACROMEER = ( kleinste contractiele
eenheid)
- CONTRACTIE = actine filamenten tussen myosinefilamenten
- RELAXATIE = actine = klein deel bedekking van myosine ( vingertjes)
- Actine filamenten niet tot midden myosine glijden = lichte zone in A-band
=H-zone
->in H-zone = condensatie myosinen = dense streep = M-streep
( mittelscheibe)
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