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Samenvatting fysiologie hoofdstuk 14
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belangrijkste zaken uit hoofdstuk 14
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Fysiologie14. Conductie van de actiepotentialen14. Conducti an actieoointaainn
14.1. Ein actieoointaaa in di eaaaos-d imins iin
Actieoointaaan irandir in v an seann in v in functi an di tid.
F i vuurn
1-2n mimbraan normaaa vieoaar isiird (ERP).
2-3n mimbraan vidieoaar isiird, maar no v ondir drimeiawaardi.
3n drimeia o irschridin.
4-5n mimbraaneoointaaa eos itif.
5-6n mimbraan rifracoa ir (actieoointaaa oorb ii viorokki)n Na + kanaain viïnact iird in vK
no v irhoo vd actieoointaaa aooeo n iio oiru v.
No v naar a inksn mimbraan oiru v normaaa vieoaar isiird.
14.2. Lokaai sorominn
Acti i zonin eaaaos waar di mimbraaneoointaaa eos itif isn door oeinsoaandi Na +
kanaain nito soroom naar b innin.
Inwind i vi ax iaai soroom aas 2 eaaaosin an aan vwire i v ciadiia iin irsch iaaindi
mimbraaneoointaaa iroonin.
Lokaai sorominn ax iaai soroom aoi i u io hio acti i vib iid in bi idi r ichtn vin in di
u iowaarosi mimbraansoroom in u iowind i vi ax iaai soroom aoi i naar hio acti i vib iid.
Inoraciaauaa iri ax iaai soroom vidra vin door K+ ionin.
Exoraciaauaa iri ax iaai soroom vidra vin door Na + ionin.
Frono actieoointaaan u iowaarosi mimbraansoroom caeac itif ( inductif)n inoraciaauaa iri
K+ ionin accumuairin oe di no v ni vati i b inninz iidi an di ciamimbraan,
ixoraciaauaa ir Na+ ionin aoi iin wi v naar hio acti i vib iid ooi.
Lokaai sorominn bas is oor viai id in vn ax iaai soroom o irschoo actieoointaaa oe
bieaaadi eaaaos door vi vi in naar nabur i vi eaaaos mimbraaneoointaaa bo in drimeia
vidieoaar isiird Na+ kanaain viact iird ook daar fuaa s izi actieoointaaa.
Oemirk in vn
Lan vwire i vi muatciaauaa iri sorucourin ciaain ia vae iunctis iaikor isch vikoeeiad
ax iaai soroom inwind i v doorhiin oeinsoaandi vae iunctoniai kanaain
mimbraaneoointaaa an nabur i vi cia ooo dieoaar isati.
14.3. Facoorin d ii di sniahi id an eroea vati biïn aoidinn
Grooiri ain voiconsoanoi λ aokaai eoointaaa irandir in v irseri id o ir vrooiri afsoand.
Sniahi id han vo af an di tidsconsoanoi τ an di mimbraan.
Hoi vrooir λ, hoi sniaair di conducti in hoi vrooir τ, hoi ora vir di conducti.
14.3.1. Biïn aoid in v an di aokaai soroom aoi in
Voorwaardi oor eroea vatin oeoridin aokaai soromin, ondirbrikin an di soroomkr in v
oor viai id in v sooeo. B ii afwiz i vhi id aad in vsdra virsn ixoraciaauaa iri ax iaai soroom aoi i
ondirbrokin, viin oor viai id in v.
Inwaarosi Na+ soroom (comeonino an aokaai soroom-c ircu io)n hoi vrooir Na + soroom, hoi
vrooir di ax iaai soromin + u iowaarosi mimbraansoroom (I C) aan hio frono an di
actieoointaaa.
Inoins ioi io Na+soroomn bieaaad sniahi id waarmii mimbraan wordo vidieoaar isiird
(sniahi id iirsoi fasi actieoointaaa).
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