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Samenvatting fysiologie hoofdstuk 11
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Fysiologie 11. Actieve eigenschappen van prikkelbarecellen: de actiepotentiaal
11. Activi iiginschappin van prikkibaari cibbin: di actippointaab:
11.1. Inbiiding:
Liniairi iiginschappin van prikkibaari cib: iin kbiini sorppm wprdo giïnjicoiird.
Er pnosoaao iin passiivi dippbarisati.
Niio-biniairi iiginschappin van prikkibaari cib: iin grpoi sorppm wprdo giïnjicoiird.
Di mimaraanppointaab wprdo apvin iin drimpibwaardi pf ohrishpbd gidippbarisiird, di
ppointaabvirandiring virhpado zich niio miir opo di grppti van di giïnjicoiirdi sorppm:
di actippointaab.
Virbppp van iin actippointaab:
Ziir snibbi dippbarisati waaraij hij ppsitif wprdo: pvirshppo.
Snibbi rippbarisati waaraij tjdibijk miir nigatif dan in rastpisoand: andirshppo.
Niimo zijn pprsprpnkibijki waardi wiir aan.
Figaar:
Eiginschap van iin actippointaab:
Di virdir gibiiding van iin actippointaab giaiaro zpndir afzwakking pmdao di
ppointaabvirandiring oibkins ppniiaw giginiriird wprdo.
Exioiiraaarhiid is iin inorinsiiki mimaraaniiginschap van ibikorisch prikkibaari cibbin: in
anowpprd pp vpbdpindi grpoi stmabi iin actippointaab pnosoaao.
11.2. Onosoaan van di actippointaab:
11.2.1. Thiprii:
Di mimaraanppointaab wprdo aipaabd dppr: Na+ in K+ pirmiaaibioiioin pf cpndacoantis.
Em in raso: dicho aij EK: K+ pirmiaaibioiio >> Na+ pirmiaaibioiio.
Em pp di opp van di actippointaab: dicho aij ENa: Na+ pirmiaaibioiio >> K+ pirmiaaibioiio.
Di mimaraan mpio pvirschakibin van hiib pirmiaaib vppr K + naar pirmiaaib vppr Na+.
Hpgkin in Haxby:
Hyppohisi dao ir iin ppointaab-afankibijki virandiring is in Na + pirmiaaibioiio van di
cibmimaraan.
Figaar:
Virkbaring van di snibbi dippbarisati van actippointaab (ixpbpsiif prpcis):
Ein dippbarisati virpprzaako iin opinami van Na + cpndacoanti inwaarosi Na+ sorppm
(INa) mimaraanppointaab dippbarisiiro virdir opinami van Na+ cpndacoanti …
Indiin hio prpcis niio afgizio zpa wprdin zpa pp aaopriginirativi wijzi di
mimaraanppointaab opo aan di ENa wprdin giaracho.
Virkbaring van di snibbi rippbarisati van actippointaab:
Afzitin van hio sysoiim.
Spanningsafankibijki opinami van di K+ cpndacoanti. Dppr di pvirshppo is di Em vir
virwijdird van di EK, zab aij opinami van gK iin aibangrijki aiowaarosi K+ sorppm
pporidin dii di mimaraanppointaab snib naar zijn pprsprpnkibijk waardi aringo.
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