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UNE Biochemistry – Questions With Accurate Answers
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UNE Biochemistry – Questions With Accurate AnswersWhich of the following enzymes is involved in the non-oxidative portion of
the Pentose Pathway? Correct Ans - Transaldolase
responsible for the transfer of 3 carbon units between sugars in the non-
oxidative portion of the pentose phosphate pathway.
Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and
glyceraldehyde 3-phosphate is facilitated by which enzyme? Correct
Ans - aldolase
fructose 1 - phosphate is cleaved by aldolase B and these products can
enter directly into the glycolytic pathway
which of the following are the two primary products of the pentose
phosphate pathway? Correct Ans - Ribose - 5- phosphate and
NADPH
the primary role of the pentose phosphate pathway is to generate 5 -
carbon sugars for nucleotide synthesis and NADPH for reductive
biosynthesis
Aldolase B facilitaes a reaction that cleaves fructose 1-phosphate into two 3
- carbon molecules that will enter glycolysis as which of the following
compounds? Correct Ans - Glyceraldehyde 3 - phosphate
fructose 1-phosphate is cleaved by aldolase B and these products can enter
directly into the glycolytic pathway. The two products produced in this
reaction are dihydroxyacetone-phosphate and glyceraldehyde
A family presents for genetic counseling. The couple has two female
children who are alive and well; however, their infant sone recently died in
the nursery with evere hemolysis (lysis of red blood cells) and jaundice.
The wife recalls she lost a brother in infancy with severe hemolysis,
induced after a viral infection. The physician suspects a glucose-6-
phosphate dehydrogenase deficiency, this would result in a deficiency in
which of the following compounds in red blood cells? Correct Ans -
Ribose and NADPH
, An 18 - month- old is newly diagnosed with hereditary fructose intolerance
(deficiency in Aldolase B). His mother reports he is particularly upset when
he gets up in the morning or if he has not eaten in a while. Laboratory
testing showed low blood glucose levels at the time of presentation. This
presentation is likely due to an accumulation of fructose 1-phosphate and
inhibition of which of the following pathways? Correct Ans -
Gluconeogenesis and glycogenolysis
Hereditary fructose intolerance can cause bouts of hypoglycemia due to
reduced activity of both gluconeogenesis and glycogenolysis
a 9-month-old girl is suffering from vomiting, lethargy, and poor feeding
behavior. her mother reports that the symptoms began shortly after the
baby was given some cereal and mashed bananas by her grandparents. the
baby's symptoms seemed to resolve after breastfeeding was resumed.
which of the folloing is the most likely diagnosis? Correct Ans -
intolerance to dietary fructose
most likely cause is the introduction of fructose into the diet. then the
fructose was removed the symptoms resolved. as breastmilk contains
lactose which is glucose and galactose it is not likely that there is an
intolerance to either glucose or galactose
Red blood cells lack mitochondria; therefore glucose is primarily oxidized
to ribose and which of the following compounds? Correct Ans -
lactate
glycolysis and the pentose phosphate pathway arethe two active pathways
for glucose catabolism in the red blood cells
which of the following enzymes is involved in the non-oxidative portion of
the pentose pathway? Correct Ans - transaldolase
transaldolase is responsible for the transfer of 3 carbon units between
sugars in the non-oxidative portion of the pentose phosphate pathway.
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