Condensed class notes for lectures about thermodynamics for biological sciences. Includes entropy, hydrophobic effects, protein folding , and Gibbs free energy.
livinggEnergy Exciting
Arrosm is an in THAT o Can
open System
· Surroundings
master mod mos
AH
atzing
A could BE : =
Ein
System Enthalpy
-
I
A Brochemical RXN MEASURES How Much
-
Energy
is
PATHWAY REgUrrED By
-
A METABOLIC A
process .
Lost Heat
SSS & -
An individual cell AHO is Favourable
↳· ·
A WHOLE THE Of OH DETERMINED
By
-
VIVE
Organism
L
Is
·
8 ↑⑳
o -
S
-
of Bonds As
⑳
L
v
THE
N umber WELL As
--
·
Biods for BONd Types
Building
. MEASURED In JONES .
Biosynthesis
AS of Disorder AH <0
chang System LosEs HEA
=
Ein
Entropy Entropy is a Measure
-
OR RANDOMNESS "THE .
UNNERSE TENdS TOWArd CHAOS" An INCREASE
. In
Entropy is =
ExOTHERMIC
THERMODYNAMICALLY FAVOURABLE WHE A dECREASE In Enropy is Not . RECALL
MOLECUTES
NORPOLAR
IN WHER
AHO
SYSTEM TAKES HEAL from
of
Surrardnungs
WHEN A
SYSTEM RELEASES HEAT , i RANSES THE Entropy THE
=
Would Be of composer Endothermic
Surroundings
A SIMILAR CASE The
Aggreghrow
.
MOLECULES WATER : WHOLE THE is a decrease
Aggregation
In
... of the HO
↑ &
· surrounding
o
.
-
Evropy The
in morecues
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:
.
.....
②.... "no"
E
· ,
·
·
- 86 --- ....
%e
..........
...
-
g
:
INCREASES As MOTOw is LESS RESTRICTED
Biological Thermodynamics
folding
THERMODYNAMICS Of PROTEIN
·
·
Hydrophilic
·
Hydrophobic
proteins Hate
&
High
Evropy
[
WATER HAS LOW
Entropy
- Due To
Hydrophobic
Effects
SO S> E
WHER
PROTEINS
·mon
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WATER Has
·
· ·
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⑨
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⑧ ·o
· Proteins Have
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⑧
·...
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o
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⑧
WATER AS7O PROTEINS ASSO
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