UNE Biochem Unit 2 Exam Quizzes & Answers

UNE Biochem Unit 2 Exam Quizzes & Answers Glycolysis provides intermediates that can be used to make other necessary substrates. One example of this is the direct conversion of pyruvate to which of the following amino acids? a. proline b. threonine c. glutamate d. alanine alanine Which of the following best describes the net effect of the 8 steps of the TCA cycle? a. this process completely oxidizes an acetyl group to carbon dioxide b. this process directly converts pyruvate to succinate c. this process produces NAD+ and Q d. this process directly produces ATP for the cell this process completely oxidizes an acetyl group to carbon dioxide Pyruvate dehydrogenase complex is highly regulated. The enzyme will be most active when which of the following compounds is high? a. pyruvate b. acetyl-CoA c. NADH d. malate pyruvate After a meal, Fructose 2, 6 bisphosphate levels are elevated. This compound will allosterically activate which of the following glycolytic enzymes? a. phosphofructokinase-1 (PFK1) b. phosphofructokinase-2 (PFK2) c. hexokinase d. glycogen synthase phosphofructokinase-1 (PFK1) A 10-year old girl is swimming in a local competition. The intense exercise will increase intracellular calcium which will increase flux through the TCA cycle by stimulating the activity of all of the following enzymes except? a. pyruvate dehydrogenase complex b. alpha-ketoglutarate dehydrogenase c. isocitrate dehydrogenase d. succiante thiokinase succinate thiokinase TCA cycle intermediates are always being removed for various reasons but the cycle doesn't run out of intermediates and stop. This is because the TCA cycle can replenish intermediates through which of the following? a. from even chain fatty acids b. using anaplerotic reactions c. from acetyl CoA d. from the catabolism of heme in the spleen using anaplerotic reactions Which of the following enzymes is correctly paired with its activator? a. isocitrate dehydrogenase; NADH b. pyruvate dehydrogenase complex; pyruvate c. glyceraldehyde 3-phosphate dehydrogenase; citrate d. pyruvate kinase; citrate pyruvate dehydrogenase complex; pyruvate Which of the following reactions is commonly used to replenish intermediates of the TCA cycle? a. citrate to oxaloacetate and acetyl CoA b. glutamate to alpha-ketoglutarate c. oxaloacetate to aspartate d. pyruvate to alanine glutamate to alpha-ketoglutarate A patient is newly diagnosed with a deficiency in fructokinase. Which of the following will not be a metabolic consequence of this deficiency? a. the presence of reducing sugar in the urine b. hypoglycemia c. decrease in fructose-1-phosphate d. inability to metabolize fructose hypoglycemia Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate is facilitated by which enzyme? a. fructohydrolase b. ketolase c. aldolase d. fructokinase aldolase Aldolase B facilitates a reaction that cleaves fructose-1-phosphate into two 3-carbon molecules that will enter glycolysis as which of the following compounds? a. glyceraldehyde-3-phosphate b. acetyl CoA c. glucose 6-phosphate d. lactate glyceraldehyde 3 phosphate Which of the following cofactors is required for transketolase activity? a. biotin b. thiamine diphosphate c. pyridoxal phosphate d. NAD+ thiamine diphosphate A family presents for genetic counseling. The couple has 2 female children who are alive and well; however, their infant son recently died in the nursery with severe hemolysis and jaundice. The wife recalls she lost a brother in infancy with severe hemolysis. The physician suspects a glucose-6-phosphate