Summary
Samenvatting gasuitwisseling en transport
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deeltje over longen
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By: bramvanroost • 6 year ago
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Chapter 18 : gasuitwisseling en transport1
, Sensoren
• Om hypoxia (laag O2) en hypercapnia (verhoogd co2) te voorkomen
• Perifere chemoreceptoren
• In arteries van aorta en halsslagader
• Veranderingen in Po2, Pco2 en Ph
• Centrale chemoreceptoren
• In medulla
• Veranderingen in Ph (CO2 + H)
Aanvoer van gassen verstoort, bloedstroom verzwakt of o2 transport
ontoereikend
CO vergiftiging
• Inademing CO
• Kleurloos, smaakloos, geurloos en moeilijk te detecteren
• Onvolledige oxidatie naar CO2 door een tekort aan O2
• Milde vergiftiging: hoofdpijn, duizelig en lichthoofdig
• Grote blootstelling: toxiciteit centraal zenuwstelsel, hart en kan tot dood leiden
• Aantrekkingskracht CO voor Hb is 230X groter dan O2 voor Hb
• CO gaat binden op Hb→ HbCO → neemt plaats van O2
Alveolaire gasuitwisseling door diffusie
• Constanten
• Oppervlakte gebied
• Dikheid membraan
• Diffusie afstand
• Concentratiegradient
• Primaire factor die de gasuitwisseling beïnvloed
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