AANP-FNP exam
Hegar's sign - ANSSoftening of lower uterine segment
Chadwick's sign - ANSBluish color of cervix and vagina at 6-8 weeks
Goodell's sign - ANSSoftening of cervix at 4+ weeks
Lipids in chronic inactivity - ANSLow HDL
Lipids in under- or untreated hypothyroidism - ANSElevated total cholesterol, TG, and LDL
Lipids in chronic renal insufficiency - ANSElevated total cholesterol and TG
Lipids in alcohol abuse - ANSElevated TG, HDL, and LDL
Vaccines with live attenuated viruses - ANSMMR, varicella, flu-mist(intranasal), Zostavax
Drugs of choice for abdominal infection - ANSBeta lactams + metronidazole (most common);
fluoroquinolones
Drugs of choice for urinary tract infection - ANSFluoroquinolones (except moxi), TMP-SMX,
fluconazole, b-lactams, nitrofurantoin, fosfomycin if pt has many allergies
Drugs of choice for pulmonary infections - ANSMacrolides, resp fluoroquinolones, b-lactams,
doxycycline (MRSA, atypical coverage)
Drugs of choice for skin and soft tissue infections - ANSMRSA: TMP-SMZ, doxycycline,
clindamycin; b-lactams
Drugs of choice for MRSA - ANSVancomycin, daptomycin , linezolid, TMP-SMZ, doxycycline,
ceftaroline
Macrolide drugs - ANSErythromycin, clarithromycin, azithromycin
Macrolide AEs - ANSGI, QT prolongation
Tetracycline uses - ANSMRSA, rocky mtn spotted fever, atypicals (mycoplasma pneumonia,
chlamydia), spirochetes (Lyme), h.pylori
Tetracycline AEs - ANSGI, teeth, hepatic dysfunction, photosensitivity
, Fluoroquinolone drugs - ANSCiprofloxacin, levofloxacin, moxifloxacin
Fluoroquinolone uses - ANSUTI (cipro or levo), atypicals (mycoplasma, legionella)
Fluoroquinolones and dairy or vitamins - ANSTake 2 hrs before or 4 hours after (decrease
concentrations)
Metronidazole (Flagyl) uses - ANSC. Diff, vaginitis
Metronidazole AEs - ANSGI, peripheral neuropathy, disulfiram reaction
Nitrofurantoin uses - ANSUTI -not pyelonephritis due to no systemic absorption
Nitrofurantoin AEs, contraindications - ANSPulmonary fibrosis, contraindicated in CrCl <60
(excludes many elderly)
Aminoglycoside drugs - ANSGentamycin, tobramycin
Aminoglycoside uses - ANSAtypical coverage, resistant infections, tobramycin for CF only
Aminoglycoside AEs - ANSOtotoxicity (irreversible), nephrotoxicity (reversible)
Aminoglycoside monitoring - ANSRenal dose adjust, hearing test, drug level monitoring
Antifungals (azoles) - ANSFluconazole, itraconazole
Itraconazole interactions - ANSAcid suppressive therapies
Fluconazole dose adjust - ANSRenal
Antifungal AEs - ANSGI, QTc prolongation (fluconazole)
Antifungal drug interactions - ANSQT prolongation meds, warfarin
Anti-infectives not for pregnant - ANSTetracyclines, TMP-SMZ
TMP-SMZ coverage - ANSG+, G-, MRSA, Protozoa (toxoplasma gondii), fungus (pneumocystis
jirovecii), poor anaerobic activity
TMP-SMZ AEs - ANSSulfa allergy, photosensitivity, hematologic (anemia, leukopenia,
thrombocytopenia)
TMP-SMZ on renal function - ANSDose adjust in renal impairment, false elevation in serum Cr