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Samenvatting Histologie
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Een samenvatting van de histologie van het bindweefsel, kraakbeen, spierweefsel, botweefsel en vetweefsel. (prof D. Creytens)
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By: maximkhalenkow • 4 year ago
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Histologie bindweefselBindweefsel
Wat? materiaal dat cellen en organen verbindt & steun geef mechanische functe
Ontstaat uit mesenchym, afomstg uit middelste laag van embryo (mesoderm)
mesenchym = opgebouwd uit mesenchymale cellen
Functe berust op extracellulaire matrix
ECM bestaat uit:
• vezels (collageen & elastsche)
• grondsubstante
Functes bindweefsel:
• steunfunctie:
kapsels rond & trabekels in organen
pezen, ligamenten
ruimte tussen organen
bot & kraakbeen
• afweer:
barrière tegen verspreiding van bacteriën
verdediging tegen infectes dmv fagocyterende cellen
• voeding:
bindweefsel bevat bloedvaten voeding van weefsels
intermediair waarlangs voedings- & afvalstofen worden uitgewisseld
Samenstelling bindweefsel:
• cellen: fbroblast, adipocyt, plasmacel, lymfocyt, eosinofele granulocyt, neutrofele
granulocyt, macrofaag, mestcel, dendritsche cel (Langerhanscel)
Fibroblast:
= meest algemeen voorkomende bindweefselcel
Produceren collageen- & elastsche vezels + glycosaminoglycanen &
glycoproteïnen v grondsubstante
Acteve fibroblasten: grote cellen met grote acteve euchromatsche kern &
uitgesproken cytoplasma
EM: kern = ovaal, groot, licht gekleurd (euchromatne), grote nucleolus, rijk
aan RER, goed ontwikkeld Golgi, slanke mitochondriën
Inacteve fbroblasten = fibrocyten: kleine cellen met kleine
heterochromatsche kern & minder cytoplasma
EM: kern = klein, langwerpig, donker gekleurd (heterochromatne), weinig
ontwikkeld RER en Golgi
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