ATI TEAS 7 ANATOMY AND PHYSIOLOGY SCIENCE EXAM GUIDE AND PREPARATIONS Science Cell Ø Cell: basic organizational unit of all living things. One thing in common is they all have membranes (phospholipids). Ø Cell structure organization: All cells contain DNA, and RNA & can synthesize proteins. Consists of nucleic acids, cytoplasm, and cell membrane. oTissues: Cells that are grouped together oOrgans: Tissues that are grouped together oSystems: Organs that are grouped together oOrganism: A complete individual Ø Nuclear parts of a cell oNucleus: contains chromosomes, & regulates DNA of the cell. Defining structure of eukaryotic cells (they all have nucleus). Passes genetic traits between generations. Contains nuclear envelop, nucleoplasm, nucleolus, nuclear pores, chromatin, & ribosomes. oChromosomes: thread like rods of DNA. Short deoxyribonucleic acid, DNA is the genetic material that stores information about the plant/animal. oChromatin: DNA & Protein makeup chromosomes oNucleolus: Proteins, small/round doesn’t have membrane. Protein synthesis, synthesizes & stores RNA. oNuclear envelope: Encloses structures within nucleus. Made of lipids. oNuclear pores: Exchange materials between the nucleus * cytoplasm oNucleoplasm: Liquid like cytoplasm, within nucleus. Cell Membranes Ø Cell Membrane (Plasma membrane): Semipermeable membrane of lipids and proteins. Made of phospholipid bilayer, hydrophilic ends of the outer layer facing the external environment, the inner layer facing inside the cell, hydrophobic ends facing each other. oHydrophilic: Water loving, can dissolve water oHydrophobic: Hates water, can’t dissolve water Ø Selective Permeability oSelective Permeability with regards to size, charge, and solubility. Ø Cell structure oRibosomes: synthesize proteins from amino acids. oGolgi apparatus: synthesize materials like proteins that are transported out of the cell. Near nucleus & consists of layers of membranes. oVacuoles: Sacs used for storage, digestion, and waste removal. One large in plant cells/ Animal cells are small or have numerous. oVesicle: Has membrane, & can move materials within the cell. oCytoskeleton: Microtubules that shape and support the cell. oMicrotubules: Part of cytoskeleton & help support cell. Made of protein. oCytosol: Liquid material within the cell. Mostly water & had floating materials. oCytoplasm: Cytosol & organelles found within the plasma membrane, not within nucleus! oCell membrane: Barrier that keeps materials out of cell. Determines what’s allowed in and out. oRough Endoplasmic reticulum: Ribosomes on the surface, produce & store proteins oSmooth Endoplasmic reticulum: Helps store lipids & proteins. oMitochondrion: Generate ATP , involved in cell growth & death. Contain their own DNA aside from the one within the nucleus. § Functions: Produce energy, cell signaling, cellular differentiation, cell cycle & growth regulation. Can also have aerobic respiration. Ø Animal Cell Structure oCentrosome: Mitosis & the cell cycle occur here oCentriole: Cellular division oLysosome: Digests proteins, lipids, and carbohydrates. Help remove undigested substances. oCilia: Appendages that cause a cell to move & can move fluid oFlagella: Tail like structures that help the cell move. A cell usually only has one or a few flagella. Longer than cilia. Ø Cell Cycle: Cell reproduces, growth cell, duplication of genetic material, and cell division. Ø Cell Differentiation: Helps determine the cell type for each cell, process is controlled by genes of each cell (zygote). Following the directions of the genes, a cell builds certain proteins and other substances to set it apart as a specific type of cell. Ø Mitosis: DNA replication & Production of new cells § IPMAT=Cytokinesis oInterphase: Cell prepares to divide by replicating genetic & cytoplasmic material. (G1, S, G2) oProphase: Chromatic thickens & nuclear membrane disintegrates. Centrioles move to opposite sides of the cells, and spindle fibers form. Mitotic spindle, formed cytoskeleton parts, moves chromosomes around the cell. oMetaphase: Spindle moves to the center of the cell. Chromosomes align in the center. oAnaphase: Sister chromosomes begin to pull apart. When separated they’re called daughter chromosomes. Grooves appear in the cell. Cell begins to furrow. oTelophase: Spindle disintegrates, nuclear membrane reform, and chromosomes turn into chromatin. In animal cells membrane is pinched, in plant cell a new cell wall begins to form. Splits into two. oCytokinesis: Physical splitting of the cell. Meiosis: Reproduction of gametes zygote